Chemical intermediates are the unsung heroes of the chemical industry, serving as crucial stepping stones in the synthesis of a vast array of end products, from life-saving pharmaceuticals to high-performance materials. Understanding these intermediates, their properties, and their applications is vital for anyone involved in chemical procurement or research. Today, we focus on a key intermediate: 1-Iodo-3,5-bis(trifluoromethyl)benzene (CAS 328-73-4).

1-Iodo-3,5-bis(trifluoromethyl)benzene is a halogenated aromatic hydrocarbon characterized by the presence of two trifluoromethyl (-CF3) groups and an iodine atom attached to a benzene ring. Its molecular formula is C8H3F6I, with a molecular weight of approximately 340.007 g/mol. Typically appearing as a clear to light yellow liquid, it is only slightly soluble in water but readily soluble in common organic solvents. This chemical profile makes it amenable to a variety of synthetic transformations.

The significance of 1-Iodo-3,5-bis(trifluoromethyl)benzene lies primarily in its role as a building block for more complex organic molecules. The iodine atom provides a reactive site for numerous cross-coupling reactions, most notably the Sonogashira coupling, where it reacts with alkynes. The trifluoromethyl groups, being highly electron-withdrawing, impart unique electronic and steric properties. These groups are known to enhance the lipophilicity, thermal stability, and metabolic resistance of molecules into which they are incorporated.

For researchers and procurement managers, identifying reliable sources for such intermediates is crucial. When you look to buy 1-Iodo-3,5-bis(trifluoromethyl)benzene, it is essential to consider manufacturers who prioritize purity and consistency. For instance, in pharmaceutical synthesis, even minor impurities can have significant consequences on the efficacy and safety of the final drug product. Therefore, seeking out suppliers who provide detailed specifications and robust quality assurance is paramount.

The applications of 1-Iodo-3,5-bis(trifluoromethyl)benzene are diverse, spanning the pharmaceutical industry for API synthesis, the agrochemical sector for developing new pesticides and herbicides, and materials science for creating novel polymers and electronic components. Its ability to readily participate in C-C bond formations, coupled with the beneficial properties of trifluoromethyl groups, makes it an indispensable intermediate for innovation.

As a dedicated supplier, we are committed to providing high-quality 1-Iodo-3,5-bis(trifluoromethyl)benzene at competitive prices. We encourage businesses and research institutions to connect with us to explore our product range and request a quote. By partnering with us, you ensure access to a reliable supply of this vital chemical intermediate, supporting your ongoing projects and future developments.