In the intricate world of chemical synthesis, understanding the fundamental properties of reagents and intermediates is paramount for successful outcomes. 1-Bromo-2-iodo-3-methoxybenzene, a compound recognized by its CAS number 450412-22-3, is a prime example of an intermediate whose chemical characteristics dictate its utility. For research scientists and product formulators, a thorough grasp of its melting point, stability, and reactivity is key to its effective application in various synthetic strategies. This article explores these properties and their direct implications for chemists looking to purchase and utilize this versatile building block.

Melting Point and Physical State: Handling Considerations
One of the primary physical properties of 1-Bromo-2-iodo-3-methoxybenzene is its melting point, typically falling within the range of 63-65 °C. This indicates that at standard room temperature, the compound exists as a solid, often described as a powder. For laboratory personnel and procurement managers, knowing this helps in planning for storage and handling. Solids are generally easier to measure and handle than liquids or gases, reducing the risk of spills and exposure. The faint to light brown color is also a visual indicator, though purity analysis via chromatography or spectroscopy is always recommended for critical applications. The stability of the compound under normal temperatures and pressures, as indicated by typical supplier information, further simplifies its management in a laboratory or production environment.

Reactivity and Synthetic Utility
The true value of 1-Bromo-2-iodo-3-methoxybenzene lies in its reactivity, largely dictated by the presence of the bromine and iodine atoms. These halogens serve as excellent leaving groups, making the molecule highly amenable to a variety of metal-catalyzed cross-coupling reactions. The differential reactivity between iodine and bromine can also be exploited; iodine is generally more reactive in oxidative addition steps with palladium catalysts than bromine. This allows for selective functionalization. For example, a chemist might perform a Suzuki coupling at the iodo position under milder conditions, then proceed with a different coupling or substitution reaction at the bromo position. This selectivity is highly desirable for constructing complex molecules efficiently. Researchers looking to buy this intermediate for complex organic synthesis will leverage these reactivity patterns to build intricate molecular scaffolds with high precision.

Implications for Procurement and Synthesis Planning
For product formulators and procurement specialists, understanding these properties directly informs purchasing decisions. When you seek to buy 1-Bromo-2-iodo-3-methoxybenzene, you are looking for a reliable source that guarantees consistent purity (often 95%+) and reliable physical form. Information regarding its predicted boiling point (around 287.1 °C) is less critical for typical handling but can be relevant for distillation or high-temperature reactions. Safety data, such as hazard statements (e.g., H315 - causes skin irritation, H319 - causes serious eye irritation), are also crucial for safe handling protocols. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide this vital information, enabling informed decisions for both laboratory chemists and procurement professionals seeking a dependable supply of this essential intermediate.

In essence, the chemical and physical properties of 1-Bromo-2-iodo-3-methoxybenzene (CAS: 450412-22-3) are not mere academic details; they are practical guides for its successful application in synthesis. By understanding these characteristics, chemists can optimize their synthetic strategies, and procurement managers can ensure they are sourcing a high-quality, reliable chemical intermediate.