In the intricate world of organic synthesis, understanding the fundamental properties and reactivity of intermediate compounds is key to successful outcomes. 1-Bromo-4-iodobutane (CAS: 89044-65-5) stands out as a highly valuable bifunctional molecule, prized for its dual halogen substitution and predictable chemical behavior. This article explores the chemical characteristics of this compound and highlights why it is a preferred choice for researchers and manufacturers in various chemical sectors.

Chemical Profile of 1-Bromo-4-iodobutane

1-Bromo-4-iodobutane is a colorless liquid with the molecular formula C4H8BrI and a molecular weight of approximately 262.91 g/mol. Its defining feature is the presence of both a bromine atom and an iodine atom at opposite ends of a four-carbon aliphatic chain. This structural arrangement dictates its reactivity and utility in synthesis:

  • Differential Reactivity of Halogens: The carbon-iodine bond is generally weaker and more reactive than the carbon-bromine bond. This difference allows for selective reactions, where the iodine can be preferentially substituted or reacted while leaving the bromine intact for subsequent transformations.
  • Nucleophilic Substitution Reactions: Both halogens can undergo nucleophilic substitution, allowing for the introduction of various functional groups such as alcohols, amines, or ethers.
  • Organometallic Reagent Formation: It can be used to form Grignard reagents or organolithium compounds, which are powerful tools in carbon-carbon bond formation.
  • Cross-Coupling Reactions: While its aliphatic nature limits direct participation in typical aryl cross-coupling, derivatives can be synthesized for such purposes, or it can be used in alkyl cross-coupling reactions.

Applications Driven by Chemical Properties

The unique reactivity of 1-Bromo-4-iodobutane makes it an indispensable tool for chemists aiming to synthesize complex organic molecules. Its utility is particularly noted in:

  • Pharmaceutical Intermediates: Facilitating the synthesis of drug molecules with precise structural requirements.
  • Agrochemical Synthesis: Enabling the creation of effective pesticides and herbicides.
  • Research and Development: A fundamental building block for exploring new synthetic methodologies and discovering novel compounds.

For those looking to purchase 1-bromo-4-iodobutane, partnering with a quality-focused organic synthesis raw materials manufacturer is essential. Ensuring a consistent supply of high-purity material from a reliable 1-bromo-4-iodobutane supplier China-based can significantly enhance your R&D and production capabilities. Understanding its chemical properties empowers chemists to leverage this compound effectively in their synthetic strategies.