4-Nitro-3-(trifluoromethyl)aniline, with CAS number 393-11-3, is a compound of significant interest within the chemical synthesis community. NINGBO INNO PHARMCHEM CO.,LTD. is a leading supplier of this versatile intermediate, renowned for its distinctive chemical properties and broad range of applications. This article aims to explore these attributes, highlighting why this molecule is a preferred choice for researchers and manufacturers in various sectors.

Characterized by its appearance as a yellow crystalline powder, 4-Nitro-3-(trifluoromethyl)aniline possesses a molecular formula of C7H5F3N2O2 and a molecular weight of 206.12. Its structure is distinguished by an aniline ring featuring a nitro group (-NO2) at the para position and a trifluoromethyl group (-CF3) at the meta position relative to the amino group (-NH2). The electron-withdrawing nature of both these substituents significantly influences the reactivity of the molecule. The nitro group deactivates the aromatic ring towards electrophilic substitution, while the trifluoromethyl group further enhances this effect and also impacts the basicity of the amino group.

These chemical properties make 4-Nitro-3-(trifluoromethyl)aniline an invaluable organic synthesis reagent. Its amine group can readily participate in a variety of reactions, including acylation, sulfonylation, and condensation, allowing for the introduction of complex side chains or the formation of heterocyclic systems. The presence of the trifluoromethyl group is particularly advantageous as it can enhance the lipophilicity, metabolic stability, and binding affinity of the final molecule, properties that are highly desirable in pharmaceutical drug discovery and agrochemical development. Consequently, it is frequently utilized as a key pharmaceutical intermediate and pesticide intermediate.

Beyond its role in pharmaceuticals and agrochemicals, 4-Nitro-3-(trifluoromethyl)aniline also finds applications in the synthesis of specialized dyes and advanced materials, where its unique electronic and structural characteristics can be exploited. NINGBO INNO PHARMCHEM CO.,LTD. ensures that this compound is supplied with high purity, typically 99%, guaranteeing reliable performance in diverse synthetic procedures. The availability of this crucial chemical intermediate supports innovation across numerous scientific disciplines.

In summary, the well-defined chemical properties and broad applicability of 4-Nitro-3-(trifluoromethyl)aniline underscore its importance in modern chemistry. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential compound, thereby supporting the advancement of research and industry through high-quality chemical solutions.