In the complex world of organic synthesis, certain compounds serve as indispensable building blocks, enabling the creation of advanced materials and high-value products. 4-Ethoxy-2,3-difluorobenzonitrile, identified by its CAS number 126162-96-7, is one such compound, highly valued for its unique chemical structure and versatile applications, particularly within the pharmaceutical and agrochemical industries. As a reputable manufacturer and supplier from China, we are pleased to delve into the specifics of this critical intermediate.

Unpacking the Chemistry: Properties of 4-Ethoxy-2,3-difluorobenzonitrile

This compound, also known by synonyms such as 4-ethoxy-2,3-difluorobenzenecarbonitrile and 2,3-difluoro-4-cyanophenetole, presents as a white to light yellow crystalline powder. Its chemical formula, C9H7F2NO, and molecular weight of 183.155 g/mol are standard benchmarks for its identity. Key physical properties that are vital for industrial handling include its density (approximately 1.2 g/cm³), boiling point (around 256.2 °C at 760 mmHg), and flash point (approximately 108.7 °C). The low vapor pressure (0.0±0.5 mmHg at 25°C) and a refractive index of 1.484 further characterize its behavior. Crucially for reliable downstream synthesis, its assay purity is maintained at a high standard of ≥98.0%.

The molecular architecture of 4-Ethoxy-2,3-difluorobenzonitrile is what lends it such significant utility. The presence of two fluorine atoms on the aromatic ring, coupled with the electron-withdrawing nitrile group and the ethoxy substituent, creates a unique electronic and steric profile. This specific arrangement dictates its reactivity, making it an attractive starting material or intermediate for various chemical transformations that are otherwise challenging to achieve.

The Role as an Organic Synthesis Intermediate

The primary function of 4-Ethoxy-2,3-difluorobenzonitrile is as an intermediate in organic synthesis. Its structure is amenable to a wide array of reactions, allowing chemists to build more complex molecules with targeted functionalities. This makes it invaluable for companies involved in the synthesis of:

  • Pharmaceuticals: As a precursor for Active Pharmaceutical Ingredients (APIs), its fluorinated nature can enhance drug stability, lipophilicity, and receptor binding affinity.
  • Agrochemicals: In the development of pesticides, herbicides, and fungicides, this intermediate contributes to creating molecules with improved efficacy, target specificity, and environmental profiles.
  • Specialty Chemicals: Beyond pharmaceuticals and agrochemicals, its unique properties can be leveraged in the creation of advanced materials and fine chemicals for various industrial applications.

As a leading manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing this high-quality intermediate. We ensure that our product meets the stringent demands of our global clientele, offering both consistency and reliability. When you need to buy 4-Ethoxy-2,3-difluorobenzonitrile, consider us as your trusted source for excellent product quality and dependable supply chain management.

Understanding the detailed chemical and physical properties of 4-Ethoxy-2,3-difluorobenzonitrile is essential for optimizing its use in synthesis. By partnering with experienced suppliers, researchers and manufacturers can ensure they obtain a product that meets their exact specifications, thereby facilitating innovation and driving successful product development.