Methyl 2-bromo-2-methylpropionate, identified by CAS number 23426-63-3, is a chemical compound that plays a significant role in various scientific and industrial applications, particularly within organic synthesis and polymer chemistry. Often supplied as a white crystalline powder by reputable manufacturers, its chemical structure endows it with specific properties that make it an invaluable reagent. This article delves into the key chemical characteristics and applications that make this compound a staple in many laboratories and production facilities.

The chemical properties of Methyl 2-bromo-2-methylpropionate are central to its utility. With a molecular formula of C5H9BrO2 and a molecular weight of approximately 181.03 g/mol, it exhibits a characteristic reactivity due to the presence of a tertiary alkyl bromide group. This functional group is prone to nucleophilic substitution and elimination reactions, making it a versatile intermediate for introducing alkyl chains or other functionalities into organic molecules. Its density is around 1.4 g/cm³, and it has a boiling point of approximately 145.8°C at atmospheric pressure, although it can be distilled at lower pressures (e.g., 52°C at 19 Torr). The flash point is reported to be around 49°C, indicating it requires careful handling due to flammability.

The most prominent application of Methyl 2-bromo-2-methylpropionate is its role as an initiator in Atom Transfer Radical Polymerization (ATRP). In ATRP, it efficiently generates radicals that initiate the growth of polymer chains, allowing for precise control over polymer molecular weight, low polydispersity, and the creation of complex polymer architectures such as block copolymers. This control is vital for developing advanced materials with specific properties for sectors like electronics, medicine, and coatings.

Beyond ATRP, this compound serves as a general intermediate in organic synthesis. It can be used in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals where the introduction of a 2-methylpropionate moiety is required. Its reactivity profile makes it a valuable component in building complex molecular structures through various synthetic pathways. For businesses seeking to purchase this essential chemical, partnering with a trusted manufacturer, especially from China, ensures access to high-purity material (≥99%) at competitive prices. Such suppliers often provide detailed technical data, including SDS and CoA, which are critical for safe and effective utilization in synthesis and research.