Trifluoroacetamide (CAS 354-38-1) is a versatile organic compound with a unique set of chemical properties that make it invaluable in various scientific and industrial applications. As a leading manufacturer and supplier of fine chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity Trifluoroacetamide to meet the demands of research and production.

Chemically, Trifluoroacetamide is an amide derived from trifluoroacetic acid. Its key properties include being a white crystalline solid with a melting point typically between 65-70°C. It exhibits good solubility in water (approximately 460 mg/ml), as well as in common organic solvents like alcohol, ether, and chloroform. This solubility profile makes it easy to handle and incorporate into various reaction systems and analytical procedures. Its molecular formula is C₂H₂F₃NO, and it has a molecular weight of 113.04 g/mol.

The primary application of Trifluoroacetamide lies in analytical chemistry, where it serves as an excellent derivatizing agent for compounds containing carboxylic acid or amine functional groups. By reacting with these groups, it forms trifluoroacetyl derivatives that are more volatile and thermally stable. This enhancement is crucial for achieving better separation and detection in techniques like Gas Chromatography-Mass Spectrometry (GC-MS). Researchers looking to buy specialized reagents for analytical purposes often turn to this compound.

In organic synthesis, Trifluoroacetamide acts as a valuable building block and reagent. It can be used as a more convenient alternative to the Gabriel synthesis for preparing primary amines from halides. Additionally, it facilitates improved N-alkylation under phase-transfer conditions, allowing for controlled sequential alkylation with different alkyl groups. These synthetic capabilities make it a key intermediate for product formulation and the development of new chemical entities. For scientists planning syntheses, understanding the price and availability from a reliable supplier is a strategic consideration.

For those seeking to purchase Trifluoroacetamide, especially in bulk quantities, partnering with an experienced manufacturer in China ensures both quality and cost-effectiveness. We at NINGBO INNO PHARMCHEM CO.,LTD. pride ourselves on delivering consistently pure products and reliable service. We encourage you to contact us for a quote and to learn more about how our Trifluoroacetamide can support your analytical and synthetic requirements.