The intricate world of catalysis often hinges on the subtle yet profound influence of ligands, molecules that bind to metal centers and modulate their reactivity and selectivity. (S,S)-DIPAMP, a prominent chiral phosphine ligand, is a prime example of how molecular design can unlock unprecedented levels of control in chemical transformations. Its unique structure and properties make it an indispensable tool for chemists engaged in asymmetric synthesis.

(S,S)-DIPAMP, with the CAS number 97858-62-3, is characterized by its white crystalline appearance and its ability to maintain stability under inert atmospheres, with a recommended storage temperature of room temperature. Its solubility in chloroform and insolubility in water are important considerations for reaction setup and workup. Furthermore, its defined melting point range (101-105 °C) and significant optical activity ([α]22/D +82) underscore its chiral integrity, a critical attribute for its function in enantioselective catalysis.

The primary application of (S,S)-DIPAMP lies in its role as a ligand in transition metal catalysts, most notably for asymmetric hydrogenation. When coordinated to metals like rhodium, it forms complexes that exhibit high activity and remarkable enantioselectivity when hydrogenating various substrates, including enamides, enol acetates, and olefins. This capability is crucial for the synthesis of enantiomerically pure compounds, which are foundational in the pharmaceutical industry for developing drugs with specific therapeutic effects and reduced side effects.

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Understanding the chemical properties of (S,S)-DIPAMP allows for its optimal utilization in complex synthetic pathways. We aim to empower our clients by providing not just the material, but also the assurance of quality and support from a trusted manufacturer.