For professionals in the chemical industry, a thorough understanding of a compound's properties and safe handling procedures is fundamental to successful and safe operations. 1-Naphthyl Isothiocyanate (CAS: 551-06-4) is an important organic synthesis intermediate, and knowledge of its characteristics is vital for anyone looking to buy or use it. This article details its key chemical properties and outlines essential handling and storage guidelines.

Chemical Identity and Physical Properties
1-Naphthyl Isothiocyanate, with the CAS number 551-06-4 and molecular formula C11H7NS, is characterized by its naphthalene ring system and the reactive isothiocyanate (-NCS) functional group. Physically, it typically presents as an off-white to yellow solid. Its melting point generally falls between 55.5-57 °C, indicating it's a solid at standard room temperature. The molecular weight is approximately 185.24 g/mol. It possesses a density around 1.1 g/cm³ and a boiling point of approximately 339.3 °C at standard atmospheric pressure, though it's often handled under reduced pressure for distillation.

Reactivity and Stability Considerations
The isothiocyanate group is known for its reactivity. 1-Naphthyl Isothiocyanate is generally stable under recommended storage conditions but is noted to be moisture sensitive. This means it can undergo hydrolysis when exposed to water, leading to decomposition. This sensitivity necessitates storage in tightly sealed containers in a dry environment. Like many isothiocyanates, it can react exothermically with incompatible materials such as strong oxidizing agents, acids, and bases. Such reactions can potentially release toxic gases, highlighting the importance of proper handling protocols and hazard assessment.

Safe Handling and Storage Guidelines
Handling:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves (e.g., nitrile or neoprene), safety goggles or a face shield, and a lab coat. Work in a well-ventilated area, preferably under a fume hood, to avoid inhalation of dust or vapors.
  • Avoid Contact: Prevent contact with skin, eyes, and clothing. In case of contact, immediately rinse affected areas with plenty of water and seek medical attention.
  • Moisture Control: Minimize exposure to atmospheric moisture during handling and transfer. Use dry equipment and inert atmosphere if necessary for sensitive applications.

Storage:

  • Container: Store in a cool, dry, well-ventilated place in tightly closed containers.
  • Temperature: Recommended storage temperatures are typically between 2-8°C, though specific requirements may vary. Always check the supplier's recommendations.
  • Incompatibilities: Keep away from incompatible materials such as strong oxidizing agents, acids, bases, moisture, and sources of ignition.

Applications and Procurement
As a crucial intermediate for organic synthesis, 1-Naphthyl Isothiocyanate is sought after by R&D scientists and manufacturers. When purchasing, it is essential to buy from reputable suppliers who provide clear specifications, Certificates of Analysis (COA), and Material Safety Data Sheets (MSDS). These documents will detail the exact purity, physical properties, and safety precautions relevant to the specific batch. Understanding these aspects ensures that users can effectively and safely integrate this compound into their processes. For bulk purchases or inquiries about price, contacting manufacturers directly, such as NINGBO INNO PHARMCHEM CO.,LTD., is recommended.

By adhering to these guidelines, users can safely and effectively utilize 1-Naphthyl Isothiocyanate in their research and industrial applications, ensuring both personnel safety and product integrity.