For scientists and chemical engineers involved in organic synthesis, a thorough understanding of the chemical and physical properties of intermediates is essential for successful and safe laboratory practices. 3-Bromo-5-nitroanisole (CAS 16618-67-0) is a compound that requires careful attention to its characteristics. As a manufacturer dedicated to providing high-quality chemical intermediates, we aim to equip our clients with the knowledge needed for effective handling and utilization of this compound. This article delves into the key properties and handling considerations for 3-Bromo-5-nitroanisole.

The physical appearance of 3-Bromo-5-nitroanisole is typically described as a brown crystalline powder. This visual cue is important for initial identification and quality checks. Its molecular formula, C7H6BrNO3, and molecular weight of 232.031 g/mol provide fundamental information for stoichiometric calculations in synthesis. The melting point, usually in the range of 86.0 to 90.0 °C, is a critical parameter for its solid-state behavior and can be indicative of its purity. Density figures, around 1.6 g/cm3, are also useful for process design and material handling calculations. These properties collectively inform how the compound will behave during weighing, dissolution, and reaction.

When considering applications and synthesis, the reactivity of 3-Bromo-5-nitroanisole is paramount. The presence of the bromine atom makes it susceptible to nucleophilic substitution and metal-catalyzed cross-coupling reactions, enabling the formation of new carbon-carbon or carbon-heteroatom bonds. The nitro group can be reduced to an amine, a common transformation in the synthesis of pharmaceuticals and dyes. Chemists seeking to buy this intermediate for specific synthetic routes should review relevant literature to fully understand its reaction profiles. As a key intermediate for organic synthesis, its correct application is vital for achieving desired product outcomes.

Handling 3-Bromo-5-nitroanisole requires adherence to standard laboratory safety protocols. Like many organic compounds, it should be handled in a well-ventilated area, preferably a fume hood, to avoid inhalation of dust or vapors. Personal protective equipment (PPE) such as gloves, safety glasses, and lab coats should always be worn. While specific toxicity data may vary, it is prudent to treat all chemical intermediates with respect and minimize direct contact. Material Safety Data Sheets (MSDS) or Safety Data Sheets (SDS) provided by reputable suppliers, including ourselves, offer detailed guidance on hazards and safe handling procedures.

Storage conditions are also important for maintaining the integrity of 3-Bromo-5-nitroanisole. It is typically recommended to store it in a cool, dry place, away from direct sunlight and incompatible materials. Proper sealing of containers prevents moisture absorption or degradation. For procurement managers and researchers looking for reliable chemical suppliers, understanding these handling and storage requirements is part of ensuring the quality and longevity of the intermediate. We ensure our packaging is suitable for preserving the quality of 3-Bromo-5-nitroanisole until it reaches your facility.

In summary, whether you are a researcher planning a synthesis or a procurement manager sourcing materials, having a solid grasp of the chemical properties and safe handling practices for 3-Bromo-5-nitroanisole is indispensable. As a leading manufacturer, we are committed to providing high-purity products along with the necessary information to support your work. If you are interested in purchasing CAS 16618-67-0, please contact us for a quote and to learn more about our product quality and services.