3-Iodotoluene (CAS 625-95-6) is a valuable organic compound used widely in chemical synthesis. For scientists and chemical engineers, understanding its specific chemical properties, alongside best practices for handling and storage, is crucial for ensuring safety and maintaining product integrity.

At room temperature, 3-Iodotoluene typically presents as a clear, colorless to pale yellow liquid. Its key identifiers include the CAS Registry Number 625-95-6 and the molecular formula C7H7I. With a molecular weight of approximately 218.04 g/mol, it is denser than water, possessing a density of about 1.698 g/cm³. The compound's boiling point is generally reported in the range of 80-82°C at reduced pressure (10 mmHg), indicating moderate volatility.

One of the important chemical properties of 3-Iodotoluene is its light sensitivity. Like many organoiodine compounds, it can degrade upon prolonged exposure to light, potentially leading to discoloration and a decrease in purity. Therefore, it is recommended to store 3-Iodotoluene in amber glass bottles or opaque containers to protect it from light. Additionally, it should be kept in a cool, dry, and well-ventilated area, away from incompatible substances.

In terms of reactivity, 3-Iodotoluene is an aryl halide. The carbon-iodine bond is relatively weak and polarizable, making it susceptible to nucleophilic substitution reactions and various metal-catalyzed cross-coupling reactions. This reactivity is precisely what makes it a sought-after intermediate in the synthesis of more complex organic molecules. However, it is also noted as being incompatible with strong oxidizing agents, which could lead to hazardous reactions.

Safe handling procedures are essential when working with 3-Iodotoluene. As indicated by its GHS hazard statements (e.g., H315 - Causes skin irritation, H319 - Causes serious eye irritation, H335 - May cause respiratory irritation, H227 - Combustible liquid), appropriate personal protective equipment (PPE) should always be worn. This includes chemical-resistant gloves, safety goggles or a face shield, and protective clothing. Work should ideally be conducted in a well-ventilated fume hood to minimize inhalation exposure.

For procurement managers and laboratory personnel, sourcing from reputable manufacturers ensures access to detailed safety data sheets (SDS) and certificates of analysis (COA). These documents provide comprehensive information on the compound's physical and chemical properties, hazards, first-aid measures, and proper storage and disposal guidelines. By adhering to these recommendations, users can safely and effectively utilize 3-Iodotoluene in their chemical processes.