4-Chlorobenzenesulfonyl Chloride (CAS 98-60-2) is a chemical compound that demands careful understanding of its properties and handling to ensure safe and effective use in industrial and research settings. As a sulfonyl chloride, it possesses inherent reactivity that makes it valuable as a synthetic intermediate but also requires specific precautions.

One of its key characteristics is its appearance: typically a white prismatic crystal. This physical state can be indicative of its purity and quality, important factors for any buyer looking to purchase this chemical. The compound is also known to be sensitive to moisture, a common trait for sulfonyl chlorides, as they can hydrolyze to form the corresponding sulfonic acid and hydrochloric acid. Therefore, proper storage conditions are crucial. Manufacturers often recommend storing it under inert gas (like nitrogen or argon) at controlled temperatures, typically between 2-8°C, to maintain its integrity and prevent degradation.

From a reactivity standpoint, 4-Chlorobenzenesulfonyl Chloride is a potent electrophile. The sulfonyl chloride group (-SO2Cl) readily reacts with nucleophiles, making it an excellent reagent for sulfonylation reactions. This reactivity is precisely what makes it so valuable in the synthesis of pharmaceuticals and agrochemicals, where the introduction of a sulfonyl moiety is often a key step. Understanding these reaction mechanisms helps chemists select it for their specific synthetic targets.

For procurement professionals and researchers looking to buy 4-Chlorobenzenesulfonyl Chloride, partnering with a reputable supplier is essential. They should be able to provide comprehensive Safety Data Sheets (SDS) detailing hazardous properties, recommended personal protective equipment (PPE), and emergency procedures. Safe handling protocols, such as working in well-ventilated areas or fume hoods and avoiding contact with skin and eyes, are non-negotiable. When considering sourcing from China, ensure your chosen manufacturer prioritizes safety and provides all necessary documentation for compliance and safe usage.