Safe and effective utilization of chemical intermediates requires a thorough understanding of their properties and handling procedures. Trifluoro-P-Tolunitrile (CAS 455-18-5), a key compound in various synthetic processes, is no exception. Ningbo Inno Pharmchem Co., Ltd. offers an overview of its essential chemical and physical characteristics, along with guidelines for safe handling.

Trifluoro-P-Tolunitrile, also known as 4-(Trifluoromethyl)benzonitrile, is an aromatic organic compound with the molecular formula C8H4F3N and a molecular weight of 171.12 g/mol. Its appearance is typically described as a colorless to pale yellow liquid. Key physical properties include a boiling point of 178-180°C at standard pressure and a melting point of -10°C. The density is recorded as 1.28 g/cm³ at 20°C, and its refractive index is in the range of 1.442-1.446 at 20°C. The flash point is 72°C (closed cup), indicating it is a combustible liquid.

Chemically, Trifluoro-P-Tolunitrile is noted for its stability under appropriate storage conditions. It is soluble in most organic solvents but insoluble in water. Recommended storage conditions are between 2-8°C under an inert atmosphere (such as nitrogen or argon) in sealed containers to maintain its integrity and prevent moisture absorption. With a shelf life of 24 months when stored properly, it is a reliable intermediate for various synthesis applications. Its CAS number, 455-18-5, serves as a unique identifier in chemical databases and for regulatory purposes.

When handling Trifluoro-P-Tolunitrile, adherence to safety protocols is paramount. As a chemical intermediate, it should be handled with appropriate personal protective equipment (PPE), including gloves, eye protection, and protective clothing. It is advisable to work in a well-ventilated area or under a fume hood to avoid inhalation of vapors. While the detailed safety data sheet (SDS) provides comprehensive information, general precautions for handling organic chemicals should be observed. Understanding the price and availability from trusted manufacturers like Ningbo Inno Pharmchem Co., Ltd. ensures that procurement is managed efficiently and safely.

In conclusion, Trifluoro-P-Tolunitrile (CAS 455-18-5) is a valuable intermediate with specific physical and chemical properties that dictate its handling and application. By understanding these characteristics and following recommended safety guidelines, users can effectively and safely incorporate this compound into their research and production processes. Ningbo Inno Pharmchem Co., Ltd. is dedicated to providing high-quality materials and information to support the safe and successful use of Trifluoro-P-Tolunitrile.