For chemists and researchers working with fine chemicals, a thorough understanding of a compound's properties and proper handling is essential for safety and successful experimentation. Trimethyl Orthobenzoate (CAS 707-07-3) is a versatile organic intermediate, and knowing its characteristics is key to its effective and safe utilization. As a dedicated manufacturer and supplier of this compound, NINGBO INNO PHARMCHEM CO.,LTD. provides insights into its chemical nature and best practices for its use.

Chemical Identity and Physical Properties:

Trimethyl Orthobenzoate, also known by synonyms such as (trimethoxymethyl)benzene or methyl orthobenzoate, has the molecular formula C10H14O3 and a molecular weight of 182.22 g/mol. It is readily identifiable by its CAS Number: 707-07-3. Physically, it presents as a clear, colorless liquid at room temperature. Key physical properties include:

  • Boiling Point: Approximately 87-88 °C at 7 mmHg, indicating a relatively low boiling point under reduced pressure.
  • Density: Around 1.061 g/mL at 25 °C, which is slightly denser than water.
  • Refractive Index: Typically measured at n20/D around 1.489, a useful parameter for quality control.
  • Flash Point: Approximately 180 °F (82 °C), classifying it as a combustible liquid.

Chemical Reactivity and Stability:

The orthoester functionality of Trimethyl Orthobenzoate makes it susceptible to hydrolysis in the presence of moisture, regenerating benzoic acid derivatives and methanol. This moisture sensitivity is a critical aspect to consider during storage and handling. Consequently, it is often stored under an inert atmosphere to maintain its integrity and reactivity. While stable under recommended storage conditions, its susceptibility to moisture means it should be handled in dry environments.

Safe Handling and Storage Practices:

Given its properties, appropriate safety precautions must be observed when working with Trimethyl Orthobenzoate:

  1. Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves (e.g., nitrile or neoprene), safety goggles or a face shield, and a lab coat. Ensure good ventilation in the work area, or use a fume hood for operations involving larger quantities or potential for aerosolization.
  2. Moisture Sensitivity: Store Trimethyl Orthobenzoate in tightly sealed containers, preferably under an inert gas such as nitrogen or argon. Avoid prolonged exposure to atmospheric moisture. When transferring, use dry equipment and minimize exposure time.
  3. Combustibility: As a combustible liquid, keep it away from open flames, sparks, and other ignition sources. Store in a cool, dry, well-ventilated area, away from incompatible materials.
  4. Incompatibilities: Avoid contact with strong oxidizing agents, strong acids, and water (unless intended for controlled reaction).
  5. Disposal: Dispose of waste material in accordance with local, regional, and national regulations. Consult the Material Safety Data Sheet (MSDS) for specific guidance.

Sourcing High-Quality Trimethyl Orthobenzoate

For reliable performance in your applications, sourcing Trimethyl Orthobenzoate from a reputable manufacturer is crucial. NINGBO INNO PHARMCHEM CO.,LTD. adheres to strict quality control measures, ensuring that our product meets purity specifications and is packaged appropriately to maintain stability. Whether you are conducting academic research or industrial-scale synthesis, we offer Trimethyl Orthobenzoate that you can trust. For detailed safety information, technical specifications, and competitive pricing for your purchase, please contact us.