For chemists and researchers working with fine chemicals, a thorough understanding of N2,N2-Dimethylpyridine-2,5-diamine (CAS 4928-43-2) is fundamental to its effective utilization. This heterocyclic compound, with its distinct pyridine core and amine substituents, possesses a range of chemical properties that dictate its behavior in various reactions and applications.

At its core, N2,N2-Dimethylpyridine-2,5-diamine is defined by its molecular formula C7H11N3 and a molecular weight of approximately 137.18 g/mol. Its appearance is often described as a blue to dark blue liquid. The molecule's structure features a pyridine ring, a six-membered aromatic heterocycle containing one nitrogen atom. This ring is substituted at the 2-position with a dimethylamino group (-N(CH3)2) and at the 5-position with a primary amino group (-NH2). This specific arrangement of functional groups is key to its reactivity.

The presence of amine groups confers basic properties to the molecule. The predicted pKa value of approximately 7.87 indicates moderate basicity, with the primary amine group being the most likely site for protonation. This property is significant when considering its behavior in acidic or basic reaction conditions. The solubility profile of N2,N2-Dimethylpyridine-2,5-diamine suggests it is moderately soluble in polar solvents, facilitated by hydrogen bonding and dipole-dipole interactions. Its LogP value of around 0.476 indicates a balance between hydrophilicity and lipophilicity, influencing its behavior in different solvent systems and biological contexts.

Safety is a critical aspect when handling any chemical. N2,N2-Dimethylpyridine-2,5-diamine is classified as an irritant, with potential hazards including skin and respiratory irritation. Researchers and industrial users should always consult the Safety Data Sheet (SDS) provided by the N2,N2-Dimethylpyridine-2,5-diamine supplier and utilize appropriate personal protective equipment (PPE) such as gloves, eye protection, and lab coats. Understanding these chemical properties allows chemists to safely and effectively incorporate N2,N2-Dimethylpyridine-2,5-diamine into their synthetic strategies or research endeavors. When purchasing, verifying the supplier's commitment to providing accurate chemical data is paramount.