Understanding the Chemical Properties of 1-(Chloromethyl)-2,3-difluorobenzene
The efficacy of a chemical intermediate lies in its inherent properties and reactivity. 1-(Chloromethyl)-2,3-difluorobenzene (CAS 446-57-1) is a compound that embodies these qualities, making it a cornerstone in many advanced synthesis pathways. NINGBO INNO PHARMCHEM CO.,LTD. provides this crucial material, understanding the detailed chemical characteristics that make it so valuable.
Structurally, 1-(Chloromethyl)-2,3-difluorobenzene presents a unique combination: a benzene ring with two fluorine atoms at adjacent positions (2 and 3) and a chloromethyl group attached to the ring. The molecular formula is C7H5ClF2, with a molecular weight of approximately 162.56. The presence of the two fluorine atoms significantly influences the electronic distribution within the benzene ring, affecting its reactivity in electrophilic aromatic substitution reactions. However, its primary utility stems from the reactivity of the chloromethyl group.
The chloromethyl moiety (-CH2Cl) is a classic electrophilic center. The carbon atom bonded to the chlorine is susceptible to nucleophilic attack, leading to the displacement of the chloride ion. This makes 1-(chloromethyl)-2,3-difluorobenzene an excellent substrate for reactions such as Williamson ether synthesis, esterification (via reaction with carboxylate salts), and amination. These reactions are fundamental for building larger, more complex organic molecules. When you need to buy 1-(chloromethyl)-2,3-difluorobenzene, consider its versatile reactivity.
For researchers and chemists, a deep understanding of these chemical properties is essential for designing efficient synthesis routes. NINGBO INNO PHARMCHEM CO.,LTD., as a reputable supplier in China, ensures that clients receive materials that meet stringent purity standards, allowing for predictable and reproducible reaction outcomes when using CAS 446-57-1. Our dedication to quality supports your critical chemical synthesis needs.
Structurally, 1-(Chloromethyl)-2,3-difluorobenzene presents a unique combination: a benzene ring with two fluorine atoms at adjacent positions (2 and 3) and a chloromethyl group attached to the ring. The molecular formula is C7H5ClF2, with a molecular weight of approximately 162.56. The presence of the two fluorine atoms significantly influences the electronic distribution within the benzene ring, affecting its reactivity in electrophilic aromatic substitution reactions. However, its primary utility stems from the reactivity of the chloromethyl group.
The chloromethyl moiety (-CH2Cl) is a classic electrophilic center. The carbon atom bonded to the chlorine is susceptible to nucleophilic attack, leading to the displacement of the chloride ion. This makes 1-(chloromethyl)-2,3-difluorobenzene an excellent substrate for reactions such as Williamson ether synthesis, esterification (via reaction with carboxylate salts), and amination. These reactions are fundamental for building larger, more complex organic molecules. When you need to buy 1-(chloromethyl)-2,3-difluorobenzene, consider its versatile reactivity.
For researchers and chemists, a deep understanding of these chemical properties is essential for designing efficient synthesis routes. NINGBO INNO PHARMCHEM CO.,LTD., as a reputable supplier in China, ensures that clients receive materials that meet stringent purity standards, allowing for predictable and reproducible reaction outcomes when using CAS 446-57-1. Our dedication to quality supports your critical chemical synthesis needs.
Perspectives & Insights
Molecule Vision 7
“, as a reputable supplier in China, ensures that clients receive materials that meet stringent purity standards, allowing for predictable and reproducible reaction outcomes when using CAS 446-57-1.”
Alpha Origin 24
“The efficacy of a chemical intermediate lies in its inherent properties and reactivity.”
Future Analyst X
“1-(Chloromethyl)-2,3-difluorobenzene (CAS 446-57-1) is a compound that embodies these qualities, making it a cornerstone in many advanced synthesis pathways.”