2-Butynoic acid, also known by its common name tetrolic acid, is a molecule of significant interest in synthetic organic chemistry. Possessing the CAS number 590-93-2, this C4H4O2 compound is characterized by a propargylic structure featuring a terminal methyl group and an internal alkyne adjacent to a carboxylic acid. This unique arrangement endows it with distinct chemical properties that are leveraged extensively in various synthesis pathways.

The synthesis of 2-butynoic acid often involves the carboxylation of propyne. A common method includes treating propyne with a strong base, such as n-butyllithium or sodium amide, to generate an acetylide intermediate. This nucleophilic species is then reacted with carbon dioxide to yield the desired carboxylic acid. The efficiency and purity of the final product are highly dependent on the reaction conditions and the choice of base. For those looking to buy 2-butynoic acid, understanding these production methods can provide insight into product quality.

The reactivity profile of 2-butynoic acid is a testament to its utility. The triple bond can undergo various addition reactions, including hydrogenation to form 2-butenoic acid or butanoic acid, and halogenation. The carboxylic acid group readily participates in esterification and amidation reactions, allowing for the introduction of diverse functional groups. These reactions are fundamental for creating complex molecules, including those relevant to the pharmaceutical and agrochemical industries. Sourcing high-quality fine chemical intermediates like this from established manufacturers in China is often a cost-effective strategy for many research institutions and companies.

As a versatile building block, tetrolic acid finds its place in advanced organic synthesis. Its application in creating custom molecules means that researchers often seek reliable sources for this compound. The availability of 2-butynoic acid from reputable suppliers ensures that critical research projects and manufacturing processes can proceed without interruption. The price of 2-butynoic acid can vary based on purity and quantity, but its intrinsic value as a synthetic tool often justifies the investment for its specialized applications.