Understanding the intricate chemical properties and synthesis routes of key intermediates is fundamental for chemists and material scientists. 4-Chlorobutyryl Chloride (4-CBCl), with CAS number 4635-59-0, is a fascinating molecule that serves as a critical building block in various industrial sectors. NINGBO INNO PHARMCHEM CO.,LTD., a leading manufacturer, provides high-purity 4-CBCl, enabling its widespread use in diverse synthetic applications.

Chemically, 4-Chlorobutyryl Chloride is classified as an acyl halide. It possesses a molecular formula of C4H6Cl2O and a molecular weight of approximately 140.99 g/mol. Its physical form is typically a colorless to light yellow liquid, often with a pungent odor. Key properties include a boiling point around 173-174 °C, a density of about 1.26 g/mL, and a refractive index of 1.461. Notably, it is moisture-sensitive and reacts with water, hydrolyzing to form 4-chlorobutyric acid and hydrochloric acid. This reactivity makes it an excellent acylating agent. The efficient synthesis of 4-chlorobutanoyl chloride is typically achieved through the reaction of gamma-butyrolactone with thionyl chloride, followed by purification.

The dual functionality of 4-CBCl—the reactive acyl chloride group and the terminal alkyl chloride—opens up a broad spectrum of synthetic possibilities. It is extensively used in acylation reactions, esterifications, and the synthesis of heterocyclic compounds. Its application as a fine chemical building block is well-established, contributing to the creation of specialized molecules for various industries. The reactivity profile makes it a preferred choice when chemists need to introduce a four-carbon chain with functional handles.

Beyond its direct use, 4-CBCl is instrumental in the production of active pharmaceutical ingredients (APIs) and agrochemicals. For instance, it is a precursor in the synthesis of compounds like Fexofenadine and intermediates for pesticides. Its role in creating specialized polymer chains and resins further underscores its versatility. The ability to consistently produce and buy 4-Chlorobutyryl Chloride from a reliable supplier in China like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for maintaining the quality and efficiency of these industrial processes.

NINGBO INNO PHARMCHEM CO.,LTD. prides itself on offering high-grade 4-Chlorobutyryl Chloride, synthesized under strict quality control measures. Our commitment to providing detailed technical specifications and ensuring product consistency makes us an ideal partner for researchers and industrial manufacturers alike who rely on the precise price of 4-Chlorobutyryl Chloride and its predictable performance.