Understanding the Chemical Properties and Synthesis of Carboxymethyl Chitosan
Carboxymethyl chitosan (CAS 83512-85-0) is a chemically modified polysaccharide derived from chitosan, distinguished by the presence of carboxymethyl groups (-CH2COOH) attached to its polymer backbone. This modification is key to its enhanced properties, particularly its increased water solubility and altered chemical reactivity. NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality Carboxymethyl chitosan, essential for researchers and manufacturers looking to leverage its unique chemical characteristics.
The synthesis of Carboxymethyl chitosan typically involves the reaction of chitosan with a carboxymethylating agent, such as monochloroacetic acid, under alkaline conditions. This process can be optimized to control the degree of substitution (DS), which refers to the average number of carboxymethyl groups per anhydroglucose unit in the chitosan chain. A higher DS generally leads to better water solubility and increased negative charge density on the polymer. The deacetylation degree of the starting chitosan material also plays a crucial role in the final properties of the Carboxymethyl chitosan product. NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent synthesis protocols to deliver Carboxymethyl chitosan with precisely controlled specifications, including a high deacetylation degree (often >90%) and a significant degree of substitution (typically ≥0.8).
The resulting Carboxymethyl chitosan molecule possesses both hydroxyl and carboxyl functional groups. These groups are responsible for its versatile chemical behavior. The carboxyl groups impart anionic character and a strong capacity for ion exchange and metal chelation. The hydroxyl groups can participate in hydrogen bonding and further chemical modifications. This unique combination of functional groups makes Carboxymethyl chitosan an excellent candidate for applications requiring specific chemical interactions, such as in drug delivery matrices, as a chelating agent for heavy metals, or as a component in responsive hydrogels.
Understanding the chemistry behind Carboxymethyl chitosan is vital for its effective utilization. By providing detailed product specifications and technical support, NINGBO INNO PHARMCHEM CO.,LTD. aims to empower scientists and engineers. Whether you are exploring new synthesis routes or developing novel applications, our high-purity Carboxymethyl chitosan is an indispensable material for your advanced chemical and biochemical research. Trust NINGBO INNO PHARMCHEM CO.,LTD. for your supply of this fundamental biopolymer.
The synthesis of Carboxymethyl chitosan typically involves the reaction of chitosan with a carboxymethylating agent, such as monochloroacetic acid, under alkaline conditions. This process can be optimized to control the degree of substitution (DS), which refers to the average number of carboxymethyl groups per anhydroglucose unit in the chitosan chain. A higher DS generally leads to better water solubility and increased negative charge density on the polymer. The deacetylation degree of the starting chitosan material also plays a crucial role in the final properties of the Carboxymethyl chitosan product. NINGBO INNO PHARMCHEM CO.,LTD. ensures consistent synthesis protocols to deliver Carboxymethyl chitosan with precisely controlled specifications, including a high deacetylation degree (often >90%) and a significant degree of substitution (typically ≥0.8).
The resulting Carboxymethyl chitosan molecule possesses both hydroxyl and carboxyl functional groups. These groups are responsible for its versatile chemical behavior. The carboxyl groups impart anionic character and a strong capacity for ion exchange and metal chelation. The hydroxyl groups can participate in hydrogen bonding and further chemical modifications. This unique combination of functional groups makes Carboxymethyl chitosan an excellent candidate for applications requiring specific chemical interactions, such as in drug delivery matrices, as a chelating agent for heavy metals, or as a component in responsive hydrogels.
Understanding the chemistry behind Carboxymethyl chitosan is vital for its effective utilization. By providing detailed product specifications and technical support, NINGBO INNO PHARMCHEM CO.,LTD. aims to empower scientists and engineers. Whether you are exploring new synthesis routes or developing novel applications, our high-purity Carboxymethyl chitosan is an indispensable material for your advanced chemical and biochemical research. Trust NINGBO INNO PHARMCHEM CO.,LTD. for your supply of this fundamental biopolymer.
Perspectives & Insights
Bio Analyst 88
“This process can be optimized to control the degree of substitution (DS), which refers to the average number of carboxymethyl groups per anhydroglucose unit in the chitosan chain.”
Nano Seeker Pro
“A higher DS generally leads to better water solubility and increased negative charge density on the polymer.”
Data Reader 7
“The deacetylation degree of the starting chitosan material also plays a crucial role in the final properties of the Carboxymethyl chitosan product.”