Understanding the fundamental chemical properties and synthesis of key reagents is vital for their effective application. N-(Trimethylsilyl)acetamide (CAS 13435-12-6) is a notable organosilicon compound that serves as a versatile silylating agent in numerous chemical processes. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated manufacturer and supplier, is committed to providing high-quality N-(Trimethylsilyl)acetamide with detailed product information.

N-(Trimethylsilyl)acetamide, with the molecular formula C5H13NOSi and a molecular weight of 131.25 g/mol, is typically described as a white to light yellow crystalline powder. Its key chemical characteristic is its reactivity as a silylating agent, meaning it can transfer its trimethylsilyl group to other molecules. This reaction is crucial in organic synthesis for protecting functional groups or preparing more volatile derivatives for analysis. The compound's melting point ranges from 46-49 °C, and it has a boiling point of 84 °C at 18 mm Hg, indicating its stability under specific conditions but also its sensitivity to moisture.

The synthesis of N-(Trimethylsilyl)acetamide generally involves the reaction of acetamide with trimethylsilyl chloride in the presence of a base. This process, carried out under strictly anhydrous conditions to prevent hydrolysis, yields the desired silylating agent. Its sensitivity to moisture is a critical aspect of its handling and storage; exposure to water can lead to hydrolysis, producing acetamide and trimethylsilanol. Therefore, proper storage under an inert atmosphere is recommended. For those looking to buy N-(Trimethylsilyl)acetamide, understanding these properties ensures optimal usage.

The reactivity profile of N-(Trimethylsilyl)acetamide extends to its role in the preparation of pharmaceutical intermediates, such as Cefdinir, and its utility in analytical chemistry for GC derivatization. Its ability to act as an allyl group scavenger further demonstrates its specific applications. When considering the N-(Trimethylsilyl)acetamide price, it's important to factor in the expertise and quality control that a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. provides.

We invite you to explore the technical specifications and application potential of our N-(Trimethylsilyl)acetamide. As a reliable supplier, we are ready to assist you with your chemical needs, ensuring you receive a product that meets the highest standards for your research and production.