For professionals in the chemical industry, understanding the precise chemical properties and practical synthesis utility of compounds is fundamental to successful research and development. Pentafluorophenyl Chlorothionoformate, identified by CAS number 135192-53-9, is a compound whose unique chemical characteristics make it a valuable asset in various organic synthesis applications.

At its core, Pentafluorophenyl Chlorothionoformate is an organosulfur compound characterized by a perfluorinated phenyl ring linked to a thionoformate functional group via an oxygen atom, with a chlorine atom attached to the thiocarbonyl group. The perfluorinated phenyl ring is strongly electron-withdrawing, significantly influencing the reactivity of the entire molecule. This electron deficiency makes the thiocarbonyl carbon more susceptible to nucleophilic attack, rendering the chlorothionoformate group an effective acylating agent. This reactivity is key for researchers looking to buy Pentafluorophenyl Chlorothionoformate for specific synthetic transformations.

The compound's physical properties further define its usability. Typically appearing as a light yellow to reddish-brown transparent liquid, it possesses a density of approximately 1.635 g/mL at 25°C and a boiling point of 98-102°C at 50 mm Hg. These specifications, along with a refractive index of n20/D 1.481, are crucial data points for chemists and formulators who need to accurately measure and handle the substance. As a chemical intermediate manufacturer, ensuring these properties are consistent batch-to-batch is vital for customer trust.

The synthesis utility of Pentafluorophenyl Chlorothionoformate is broad. It is widely employed in the formation of thioesters, which are important functional groups in natural products and pharmaceuticals. Its role as a reagent in converting alcohols to thiochloroformates is a common pathway for further functionalization. Beyond this, its application in the synthesis of specific nucleoside analogues highlights its importance in medicinal chemistry and biochemistry. For anyone seeking to procure this material, understanding these synthetic pathways aids in assessing its suitability for their specific project needs.

Procurement managers and research scientists often seek a reliable supplier that can provide this compound with high purity (≥98.0%). A competitive price from a reputable manufacturer, coupled with adherence to proper storage guidelines (cool, dry, well-ventilated), ensures that the compound retains its efficacy. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated provider of Pentafluorophenyl Chlorothionoformate, committed to delivering high-quality materials that facilitate groundbreaking research and development. We encourage you to reach out for detailed specifications and purchasing inquiries.