Understanding the inherent chemical properties of key synthetic intermediates is fundamental to their successful application in research and industry. 1,3-Dibromoisoquinoline, bearing the CAS number 53987-60-3, is a prime example of such a compound, offering a unique combination of reactivity and structural versatility. NINGBO INNO PHARMCHEM CO.,LTD. is pleased to provide detailed insights into this important chemical building block.

The molecular structure of 1,3-dibromoisoquinoline features an isoquinoline core substituted with bromine atoms at the 1 and 3 positions. This dibromoisoquinoline arrangement imparts specific reactivity patterns that are highly valued in organic synthesis. Typically appearing as a white solid, it possesses a molecular weight of approximately 286.95 g/mol. Its melting point, often in the range of 145-150°C, is indicative of its solid state at room temperature. The presence of two electron-withdrawing bromine atoms can influence the electron density distribution within the isoquinoline ring, making certain positions more susceptible to nucleophilic or electrophilic attack depending on the reaction conditions.

The synthetic utility of 1,3-dibromoisoquinoline is vast. It commonly serves as a precursor in various cross-coupling reactions, which are indispensable tools for carbon-carbon bond formation. For example, palladium-catalyzed reactions like Suzuki-Miyaura or Heck couplings can be employed to replace the bromine atoms with carbon-based substituents, leading to a diverse range of functionalized isoquinolines. These functionalized derivatives are often sought after in the pharmaceutical industry for their potential biological activities. The efficiency of these reactions often depends on the purity of the starting materials, which is why sourcing high-quality 1,3-dibromoisoquinoline is paramount.

Researchers frequently utilize this compound to construct complex heterocyclic systems or to introduce specific pharmacophores into potential drug molecules. The strategic synthesis using 1,3-dibromoisoquinoline allows for the development of novel compounds with targeted properties, whether for therapeutic applications, advanced materials, or specialized fine chemicals. The ability to buy 1,3-dibromoisoquinoline that is consistently pure and reliably supplied by NINGBO INNO PHARMCHEM CO.,LTD. significantly streamlines the research and development process.

In conclusion, the chemical properties of 1,3-dibromoisoquinoline make it an exceptionally versatile intermediate for a wide spectrum of organic synthesis applications. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and manufacturers with this crucial dibromoisoquinoline derivative, ensuring access to high-quality materials that facilitate groundbreaking discoveries and efficient production. Understanding its synthetic utility is the first step toward unlocking its full potential in your chemical projects.