The Chemical Reactivity of 2,2,2-Trifluoroethyl p-Toluenesulfonate
The precise chemical reactivity of a compound dictates its utility in synthesis. 2,2,2-Trifluoroethyl p-Toluenesulfonate stands out as a highly effective trifluoroethylation agent, primarily due to the inherent properties of its constituent groups. This compound, offered by NINGBO INNO PHARMCHEM CO.,LTD., is a critical component for chemists looking to introduce the trifluoroethyl group into diverse molecular frameworks.
The reactivity of 2,2,2-Trifluoroethyl p-Toluenesulfonate stems from the excellent leaving group ability of the p-toluenesulfonate (tosylate) anion. Coupled with the electron-withdrawing effect of the trifluoromethyl group in the adjacent ethyl chain, the carbon atom of the ethyl group becomes significantly electrophilic. This makes it highly susceptible to nucleophilic attack, facilitating efficient trifluoroethylation reactions. When researchers decide to buy this reagent, they are acquiring a tool designed for specific and effective chemical transformations.
The synthesis of this compound is typically achieved by reacting 2,2,2-trifluoroethanol with p-toluenesulfonyl chloride, often in the presence of a base like pyridine. This straightforward preparation method ensures its availability for widespread use. The resulting white crystalline solid is stable under normal conditions, allowing for easy storage and handling. NINGBO INNO PHARMCHEM CO.,LTD. ensures the quality and purity of this reagent, making it a reliable choice for your chemical needs.
The applications of 2,2,2-Trifluoroethyl p-Toluenesulfonate are far-reaching. In the pharmaceutical sector, its ability to introduce the trifluoroethyl group is invaluable for enhancing drug properties such as metabolic stability and lipophilicity. This leads to the development of more effective therapeutics. Researchers seeking to buy this compound for their drug discovery programs will find NINGBO INNO PHARMCHEM CO.,LTD. to be a dependable supplier, offering competitive pricing and consistent product quality.
Furthermore, its reactivity makes it useful in the agrochemical industry for synthesizing pesticides with improved efficacy and in material science for creating advanced fluorinated materials with unique characteristics. The consistent demand for this versatile reagent underscores its importance. NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting this demand, providing high-quality 2,2,2-Trifluoroethyl p-Toluenesulfonate to support innovation across various chemical disciplines.
The reactivity of 2,2,2-Trifluoroethyl p-Toluenesulfonate stems from the excellent leaving group ability of the p-toluenesulfonate (tosylate) anion. Coupled with the electron-withdrawing effect of the trifluoromethyl group in the adjacent ethyl chain, the carbon atom of the ethyl group becomes significantly electrophilic. This makes it highly susceptible to nucleophilic attack, facilitating efficient trifluoroethylation reactions. When researchers decide to buy this reagent, they are acquiring a tool designed for specific and effective chemical transformations.
The synthesis of this compound is typically achieved by reacting 2,2,2-trifluoroethanol with p-toluenesulfonyl chloride, often in the presence of a base like pyridine. This straightforward preparation method ensures its availability for widespread use. The resulting white crystalline solid is stable under normal conditions, allowing for easy storage and handling. NINGBO INNO PHARMCHEM CO.,LTD. ensures the quality and purity of this reagent, making it a reliable choice for your chemical needs.
The applications of 2,2,2-Trifluoroethyl p-Toluenesulfonate are far-reaching. In the pharmaceutical sector, its ability to introduce the trifluoroethyl group is invaluable for enhancing drug properties such as metabolic stability and lipophilicity. This leads to the development of more effective therapeutics. Researchers seeking to buy this compound for their drug discovery programs will find NINGBO INNO PHARMCHEM CO.,LTD. to be a dependable supplier, offering competitive pricing and consistent product quality.
Furthermore, its reactivity makes it useful in the agrochemical industry for synthesizing pesticides with improved efficacy and in material science for creating advanced fluorinated materials with unique characteristics. The consistent demand for this versatile reagent underscores its importance. NINGBO INNO PHARMCHEM CO.,LTD. is committed to meeting this demand, providing high-quality 2,2,2-Trifluoroethyl p-Toluenesulfonate to support innovation across various chemical disciplines.
Perspectives & Insights
Bio Analyst 88
“Furthermore, its reactivity makes it useful in the agrochemical industry for synthesizing pesticides with improved efficacy and in material science for creating advanced fluorinated materials with unique characteristics.”
Nano Seeker Pro
“is committed to meeting this demand, providing high-quality 2,2,2-Trifluoroethyl p-Toluenesulfonate to support innovation across various chemical disciplines.”
Data Reader 7
“2,2,2-Trifluoroethyl p-Toluenesulfonate stands out as a highly effective trifluoroethylation agent, primarily due to the inherent properties of its constituent groups.”