For Research and Development scientists, a thorough understanding of a chemical's reactivity is fundamental to its effective and safe utilization. Benzoyl Chloride (CAS 98-88-4), a potent acylating agent, exhibits a characteristic reactivity profile that enables its widespread use in organic synthesis. This guide explores its key reactions, providing insights for those looking to buy this versatile intermediate from a reliable manufacturer.

One of the most well-known reactions of Benzoyl Chloride is its vigorous reaction with water. This hydrolysis yields benzoic acid and hydrochloric acid. This property necessitates anhydrous handling conditions and explains why Benzoyl Chloride is a fuming liquid when exposed to atmospheric moisture. Manufacturers typically ensure that the product is packaged and stored under conditions that prevent moisture ingress.

As a typical acyl chloride, Benzoyl Chloride readily reacts with alcohols to form esters and with amines to form amides. These reactions, often carried out under Schotten-Baumann conditions (using a base to neutralize the HCl byproduct), are crucial for synthesizing a vast array of compounds. For instance, reaction with methanol yields methyl benzoate, while reaction with aniline produces N-phenylbenzamide.

The Friedel-Crafts acylation is another significant reaction where Benzoyl Chloride serves as an electrophilic source of the benzoyl group (C6H5CO+). In the presence of a Lewis acid catalyst like aluminum chloride (AlCl3), it reacts with aromatic compounds to form substituted benzophenones. This pathway is vital for creating complex aromatic structures used in various industries, including pharmaceuticals and polymers.

Benzoyl Chloride is also a precursor to benzoyl peroxide, a widely used initiator for polymerizations. The industrial synthesis involves reacting Benzoyl Chloride with hydrogen peroxide in the presence of a base. This highlights its role not only as a direct intermediate but also as a key component in producing other essential industrial chemicals.

For R&D scientists, sourcing high-purity Benzoyl Chloride is critical for predictable and reproducible experimental outcomes. Manufacturers like us, offering 99.5% purity, ensure that the reactivity profile is consistent. When you buy Benzoyl Chloride, understanding these reactions helps in planning experimental procedures and selecting appropriate safety measures. We are your trusted supplier for quality Benzoyl Chloride for all your synthesis needs.