Understanding the fundamental properties and chemical structure of an intermediate is crucial for its effective application in synthesis. 1,1'-Methylenebis[4-fluorobenzene], designated by CAS number 457-68-1, is an organic compound that garners significant interest due to its unique molecular architecture and the influence of its fluorine substituents. This article details these aspects and guides potential buyers on how to procure this compound.

Molecular Structure and Characteristics

The chemical formula for 1,1'-Methylenebis[4-fluorobenzene] is C13H10F2, with a molecular weight of approximately 204.22 g/mol. Its structure consists of a central methylene group (-CH2-) that bridges two phenyl rings. Each phenyl ring is substituted with a fluorine atom at the para (4) position. This configuration, often referred to as 4,4'-Difluorodiphenylmethane or Bis(4-fluorophenyl)methane, is key to its chemical behavior.

The presence of electronegative fluorine atoms affects the electron distribution within the phenyl rings, influencing the compound's reactivity and its interactions in chemical reactions. These fluorinated aromatic systems often exhibit:

  • Increased Thermal Stability: Fluorine-carbon bonds are strong, contributing to higher thermal resistance.
  • Modified Reactivity: The electron-withdrawing nature of fluorine can alter the reactivity of the aromatic rings in electrophilic or nucleophilic substitution reactions.
  • Solubility Properties: While generally soluble in common organic solvents, the fluorination can subtly alter its solubility profile.

Physical Properties and Purity

1,1'-Methylenebis[4-fluorobenzene] is typically encountered as a white to pale yellow solid, which can be in powder or lump form depending on the manufacturing and packaging process. For critical applications, especially in pharmaceutical synthesis or advanced materials development, maintaining a high purity level is paramount. Many suppliers offer grades with purity exceeding 98.0% by Gas Chromatography (GC), ensuring that the material is suitable for demanding chemical processes.

Where to Purchase CAS 457-68-1

For researchers and manufacturers looking to buy 1,1'-Methylenebis[4-fluorobenzene], identifying reliable suppliers is essential. Companies specializing in fine chemical intermediates, many of whom are based in China, provide this compound with consistent quality and competitive pricing. When you plan to purchase this chemical intermediate, ensure that the supplier can provide:

  • Detailed technical specifications, including CAS number and confirmed purity.
  • A Certificate of Analysis (CoA) with each batch.
  • Appropriate packaging solutions to maintain product integrity during transport and storage.

By understanding the structural and physical properties of 1,1'-Methylenebis[4-fluorobenzene] and selecting a reputable manufacturer, you can confidently integrate this valuable intermediate into your chemical projects.