For professionals in the chemical industry, a deep understanding of the compounds they work with is crucial for successful application and procurement. 1-Bromododecane (CAS 143-15-7) is a widely used organic intermediate, and knowing its chemical synthesis routes and properties can help buyers make informed decisions. This article explores the fundamental chemistry behind 1-Bromododecane, from its production to its key physical characteristics, from the perspective of a leading chemical manufacturer.

Understanding the Molecular Structure and Properties

1-Bromododecane is a saturated haloalkane with the chemical formula C12H25Br. It features a linear twelve-carbon chain with a bromine atom attached to the terminal (first) carbon. This structure imparts specific properties: it is a colorless transparent liquid at room temperature, with a notable boiling point of approximately 276.2°C at atmospheric pressure. Its high flash point (113°C) indicates moderate flammability, and it is insoluble in water but soluble in organic solvents. The molecule's significant hydrocarbon chain renders it lipophilic, which is key to its function as an alkylating agent.

Common Synthesis Routes for 1-Bromododecane

As a manufacturer, efficient and scalable synthesis methods are paramount. Two primary routes are commonly employed for producing 1-Bromododecane:

  1. From 1-Dodecene: The most common industrial method involves the free-radical addition of hydrogen bromide (HBr) to 1-dodecene. This reaction follows an anti-Markovnikov addition pathway, ensuring the bromine atom attaches to the terminal carbon, yielding 1-Bromododecane. This method is favored for its efficiency and the ready availability of the starting alkene.
  2. From Dodecanol: Alternatively, 1-Bromododecane can be synthesized by reacting dodecanol (lauryl alcohol) with hydrobromic acid (HBr), often in the presence of a strong acid catalyst like sulfuric acid. This nucleophilic substitution reaction replaces the hydroxyl group with a bromine atom.

Both methods are refined by manufacturers to achieve high yields and the desired 99% purity level, ensuring that the product is suitable for demanding applications in pharmaceuticals, specialty chemicals, and surfactant production.

Why Chemical Buyers Should Understand Synthesis and Properties

Knowing the synthesis routes helps buyers understand potential impurities and the robustness of the manufacturing process. For instance, the anti-Markovnikov addition to 1-dodecene typically yields a cleaner product with fewer positional isomers compared to other potential routes. Understanding the properties—like its boiling point, solubility, and stability—is essential for formulators to predict its behavior in different reaction conditions and storage. When you inquire about buying 1-Bromododecane, asking about its origin and synthesis can provide valuable insights into its quality. As a leading chemical supplier, we are transparent about our manufacturing processes and product specifications.

Procurement from a Trusted Source

NINGBO INNO PHARMCHEM CO.,LTD. specializes in the manufacturing and supply of high-quality chemical intermediates. Our 1-Bromododecane (CAS 143-15-7) is produced using optimized synthesis methods to guarantee 99% purity. We cater to businesses looking for reliable suppliers in China, offering competitive prices and consistent product availability. Whether for R&D or large-scale production, we are equipped to meet your needs.

Conclusion

A thorough understanding of the chemistry behind 1-Bromododecane—its structure, synthesis, and properties—empowers buyers to make informed procurement decisions. As a key alkylating agent and intermediate, its quality directly impacts the final product. We encourage you to contact us for any inquiries regarding 1-Bromododecane, request a quote, or discuss your specific application needs with our expert team. Let us be your trusted partner for high-quality chemical intermediates.