Crown ethers, a fascinating class of macrocyclic polyethers, have revolutionized various fields of chemistry due to their unique ability to selectively bind metal cations. Among these, 15-Crown-5 (CAS 33100-27-5) is a particularly important and versatile compound, widely utilized in organic synthesis, analytical chemistry, and beyond. As a dedicated manufacturer and supplier of high-purity fine chemicals, we are committed to providing researchers and industries with comprehensive information and access to this essential reagent. Our 99% pure 15-Crown-5 is produced with precision, ensuring optimal performance for all your chemical needs.

Understanding 15-Crown-5: Structure and Properties

15-Crown-5 is characterized by its cyclic structure, comprising a fifteen-membered ring with five oxygen atoms interspersed between ethylene units. This specific arrangement creates an internal cavity whose size is ideally suited for coordinating with cations like potassium (K+). The electron-rich oxygen atoms of the ether linkages act as Lewis bases, donating electron pairs to form coordinate bonds with the positively charged cation. This complexation process effectively shields the cation's charge, enhancing the solubility and reactivity of the associated counter-anion in organic solvents. This property is the foundation of its utility as a phase transfer catalyst and in ion separation technologies.

Its physical properties include being a colorless liquid with a relatively low melting point of -20°C and a boiling point of 93-96 °C at low pressure. It is miscible with many organic solvents, further contributing to its ease of use in diverse reaction environments.

Synthesis and Manufacturing Excellence

The synthesis of 15-Crown-5 typically involves cyclization reactions, often using a diol and a dihalide or a related precursor under specific catalytic conditions. As a manufacturer, our focus is on optimizing these synthetic routes to achieve high yields and exceptional purity. We employ stringent quality control measures throughout the production process, from raw material selection to the final purification and packaging of 15-Crown-5. This dedication ensures that when you buy 15-Crown-5 from us, you are receiving a product that meets the highest industry standards, backed by reliable data and certificates of analysis.

Diverse Applications Driving Chemical Innovation

The versatility of 15-Crown-5 fuels its widespread application:

  • Phase Transfer Catalysis: It significantly enhances the rate and efficiency of reactions involving reactants in different phases, such as nucleophilic substitutions, oxidations, and reductions.
  • Ion Complexation and Separation: Its selective binding to cations makes it invaluable for ion-selective electrodes, solvent extraction processes, and chromatographic separations.
  • Organic Synthesis: It facilitates reactions like O-alkylation and Williamson ether synthesis, particularly with challenging substrates.
  • Biochemical and Medicinal Research: Used in studies related to ion channels, drug delivery, and biochemical sensing.

For professionals seeking to buy 15-Crown-5, partnering with a reputable manufacturer and supplier like us provides significant advantages. We offer not only high-purity chemicals but also competitive pricing, reliable supply, and dedicated technical support. Our commitment is to facilitate your scientific and industrial endeavors with the best possible chemical reagents.

In summary, 15-Crown-5 is a pivotal compound in modern chemistry, offering unique solutions for complex challenges. We invite you to explore its capabilities and leverage our expertise as a leading manufacturer and supplier. Contact us today to learn more about our 15-Crown-5 products and discuss how we can support your next project.