For research and development scientists pushing the boundaries of organic chemistry, understanding the utility of key building blocks is crucial. 2-Bromoethyl Isothiocyanate (CAS 1483-41-6) stands out as a versatile reagent, integral to numerous synthetic pathways and biochemical studies. Its unique bifunctional nature, combining a bromoethyl group with an isothiocyanate moiety, allows for diverse reactivity, making it a sought-after intermediate. This article delves into the chemical properties and significant applications of this compound, highlighting why it's a valuable asset in modern laboratories.

Understanding the Reactivity Profile

2-Bromoethyl Isothiocyanate is characterized by its potent electrophilic isothiocyanate group and the reactive carbon-bromine bond. The isothiocyanate group (-N=C=S) readily undergoes nucleophilic addition reactions, forming thioureas, thiocarbamates, and other sulfur-containing heterocycles. The bromoethyl chain, meanwhile, acts as an alkylating agent. This dual reactivity allows for sequential or simultaneous modification of molecules, enabling the synthesis of complex structures with tailored functionalities. As a supplier, we ensure this compound is readily available for your experimental needs.

Key Applications in Research and Synthesis

The application spectrum of 2-Bromoethyl Isothiocyanate is broad, particularly within the realms of biochemistry and advanced organic synthesis:

  • Enzyme Inhibition Studies: The isothiocyanate group is known to react with nucleophilic amino acid residues (like cysteine and lysine) in proteins. This property makes 2-Bromoethyl Isothiocyanate a valuable tool for scientists investigating enzyme mechanisms and developing enzyme inhibitors. Understanding how to buy this chemical is the first step for many such studies.
  • Protein Modification: Researchers employ this compound to covalently label proteins, allowing for fluorescence detection, immobilization on solid supports, or alteration of protein function. This is crucial in fields like proteomics and structural biology.
  • DNA Sequencing and Cellular Research: Its reactivity profile also lends itself to applications in DNA sequencing methodologies and as a probe in cellular response studies, helping researchers understand biological processes at a molecular level.
  • Heterocyclic Synthesis: As a fundamental building block, it is widely used in the synthesis of various sulfur- and nitrogen-containing heterocyclic compounds, which are common motifs in pharmaceuticals and agrochemicals. Many scientists are keen to learn the price of such key intermediates.

Sourcing with Confidence

For any scientist or procurement specialist looking to purchase 2-Bromoethyl Isothiocyanate, partnering with a reputable manufacturer and supplier is essential. A reliable source ensures product consistency, adherence to specifications (such as its colourless to yellow liquid appearance), and timely delivery. Many R&D labs actively search for 'where to buy 2-bromoethyl isothiocyanate in China' due to the country's strong chemical manufacturing base. When inquiring, always request a quote that details purity and packaging, and confirm the CAS number (1483-41-6) to guarantee you are receiving the correct chemical.

The ability to efficiently and reliably obtain compounds like 2-Bromoethyl Isothiocyanate empowers scientific innovation. By understanding its chemical versatility and sourcing it from trusted manufacturers, researchers can accelerate their discovery processes.