In the complex world of chemical synthesis, understanding the origin and properties of key intermediates is fundamental. 2-Phenylindole (CAS 948-65-2) is one such compound, recognized for its significant utility in industries ranging from plastics to textiles. This article explores its synthesis, chemical characteristics, and the industrial importance that makes it a sought-after product from reliable chemical manufacturers.

Synthesis and Chemical Structure

2-Phenylindole is an organic compound with the molecular formula C14H11N. Its structure features an indole core with a phenyl group attached at the 2-position. Common synthetic routes include the condensation of phenylhydrazine with acetophenone, followed by ring closure catalyzed by agents like zinc chloride. Alternative methods, such as heating bromoacetophenone with aniline, also yield this valuable intermediate. The meticulous control over these synthesis pathways ensures the high purity (typically ≥98.0% assay) required for its industrial applications.

Key Properties and Appearance

The typical appearance of 2-Phenylindole is a pale white to beige or greenish powder. Its key properties include:

  • Molecular Weight: Approximately 193.24 g/mol
  • Melting Point: Around 188-190 °C
  • Boiling Point: Approximately 250 °C at 10 mmHg
  • Assay: Generally available at ≥98.0% purity.

These precise specifications are crucial for formulators and researchers aiming to achieve specific results in their chemical processes.

Industrial Significance and Applications

The industrial demand for 2-Phenylindole is driven by its dual role:

  • PVC Cellophane Stabilizer: Its ability to enhance the thermal and light stability of PVC makes it an important additive in the plastics industry.
  • Dye Intermediate: It is a critical precursor in the synthesis of numerous cationic dyes, which are vital for coloring textiles, inks, and other materials. The consistent quality of 2-Phenylindole directly impacts the vibrancy and fastness of these dyes.
  • Research and Development: The compound is also employed as a reactant and building block in academic and industrial research for developing novel organic compounds and materials.

Sourcing 2-Phenylindole: Partnering with Suppliers

For businesses needing to buy 2-Phenylindole, sourcing from established suppliers and manufacturers is essential for ensuring quality and competitive pricing. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing high-purity 2-Phenylindole, offering reliable supply chains and technical support to clients worldwide. When evaluating potential suppliers, consider their adherence to quality standards, production capacity, and transparency in their pricing and logistical processes. Engaging with an experienced chemical partner ensures you can procure this vital intermediate efficiently and effectively.