At NINGBO INNO PHARMCHEM CO.,LTD., we believe in providing our clients with not just chemicals, but also comprehensive knowledge about their applications. Today, we focus on 9-Fluorenemethanol (CAS 24324-17-2), exploring its fundamental chemical properties and its significant role as a protecting group.

9-Fluorenemethanol, with the molecular formula C14H12O and a molecular weight of 196.24, presents itself typically as a white to pale yellow crystalline powder. Its melting point, generally recorded between 105-107°C, signifies its solid state at room temperature. These physical attributes are important for handling and storage, ensuring stability for its use in sensitive chemical processes.

The primary chemical function that makes 9-Fluorenemethanol so valuable is its efficacy as a protecting group. Specifically, it is widely employed as a carboxy protecting group and a phosphate protecting group. In the synthesis of complex molecules, such as peptides and oligonucleotides, certain functional groups need to be temporarily masked to prevent them from reacting prematurely or undergoing unwanted transformations. 9-Fluorenemethanol achieves this by forming stable derivatives, such as 9-fluorenylmethyl esters.

The key advantage of using 9-Fluorenemethanol lies in the cleavability of these derivatives. The 9-fluorenylmethyl esters can be readily removed under mild basic conditions, for instance, using piperidine. This characteristic allows for selective deprotection, a critical requirement in multi-step syntheses where different protecting groups might be employed simultaneously. This orthogonality ensures that chemists can precisely control which functional groups are revealed and when, thus managing the complexity of the synthesis.

For researchers looking to buy 9-fluorenemethanol, understanding these chemical properties is essential for successful experimental design. The reliable performance of 9-fluorenemethanol in both peptide synthesis and oligonucleotide construction underscores its importance. As leading 9-fluorenemethanol suppliers, NINGBO INNO PHARMCHEM CO.,LTD. ensures that the CAS 24324-17-2 product we provide meets high standards of purity and consistency, supporting the critical work of scientists.

In conclusion, the well-defined 9-fluorenemethanol chemical properties, particularly its role as a versatile and cleavable protecting group, make it an indispensable tool in the arsenal of synthetic chemists across various disciplines.