N-Methylformamide (NMF), bearing the CAS number 123-39-7, is a fundamental organic compound characterized by its colorless, transparent liquid appearance. Its significance in the chemical industry stems from its dual role as a highly effective organic solvent and a crucial chemical intermediate. For professionals in fields ranging from pharmaceuticals to agrochemicals, a thorough understanding of NMF's synthesis pathways and inherent chemical properties is essential for effective utilization and procurement.

Synthesis of N-Methylformamide

The production of N-Methylformamide typically involves the reaction of methylamine with a formic acid derivative. Common methods include:

  • Reaction with Formic Acid: Methylamine reacts with formic acid, often under controlled conditions that facilitate dehydration, to yield N-Methylformamide and water. The process requires careful management of reaction parameters to maximize yield and purity.
  • Reaction with Methyl Formate: Alternatively, methylamine can react with methyl formate. This reaction yields N-Methylformamide and methanol as a co-product. The choice of synthesis route often depends on raw material availability, cost-effectiveness, and desired purity levels.

Following synthesis, purification steps such as distillation are employed to isolate high-purity NMF, ensuring it meets the stringent requirements for industrial applications, often exceeding 99.5% purity.

Key Chemical and Physical Properties

N-Methylformamide's utility is rooted in its distinctive properties:

  • Appearance: Colorless transparent liquid.
  • Purity: Typically available at ≥99.5% assay.
  • Solvency: Acts as a powerful solvent for a wide range of organic and inorganic compounds.
  • Thermal Stability: With a boiling point around 180-185 °C, it can be used in high-temperature reaction processes.
  • Versatility: Functions effectively as both a reaction solvent and a purification solvent in organic synthesis.
  • Intermediate Role: Serves as a building block for synthesizing more complex organic molecules, including those used in pharmaceuticals and agrochemicals.

Procuring Quality N-Methylformamide

To leverage these properties effectively, it is vital to buy N-Methylformamide from a reliable manufacturer. We pride ourselves on being a leading supplier of high-purity NMF, offering consistent quality and a stable supply chain. Our manufacturing capabilities ensure that you receive N-Methylformamide that meets your exact specifications, whether for pharmaceutical synthesis, agrochemical production, or other industrial uses. Contact us to learn more about our NMF pricing and to secure a dependable source for this essential chemical.