The Chemistry Behind Z-Pyr-OSu: A Versatile Intermediate for Synthesis
The efficacy of complex chemical syntheses often hinges on the selection of appropriate intermediate compounds. Z-Pyr-OSu (CAS: 40291-26-7) exemplifies such a crucial intermediate, widely utilized for its specific chemical reactivity. NINGBO INNO PHARMCHEM CO.,LTD., a distinguished chemical manufacturer and supplier operating from China, is at the forefront of providing high-quality Z-Pyr-OSu, supporting advancements across various scientific disciplines.
At its core, Z-Pyr-OSu is defined by its unique chemical structure, which combines a protected pyroglutamic acid moiety with an N-hydroxysuccinimide (NHS) ester. The 'Z' in Z-Pyr-OSu refers to the benzyloxycarbonyl (Cbz) protecting group on the pyroglutamic acid, a common feature in peptide synthesis to control reactivity. The NHS ester is a highly efficient leaving group, rendering the adjacent carbonyl carbon susceptible to nucleophilic attack. This structural design makes Z-Pyr-OSu an excellent agent for activating carboxylic acids, facilitating the formation of amide bonds with amine-containing molecules. This property is particularly leveraged in solid-phase peptide synthesis (SPPS) and solution-phase coupling reactions.
The reactivity of Z-Pyr-OSu allows for controlled conjugation, making it valuable in applications beyond basic peptide elongation. It is instrumental in creating customized peptides, modified amino acids, and linking biomolecules for therapeutic or diagnostic purposes. For researchers and procurement specialists, sourcing Z-Pyr-OSu from a reliable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is paramount. Our commitment to quality ensures that you receive a product with consistent reactivity and purity, vital for reproducible results. We actively encourage inquiries regarding Z-Pyr-OSu price and bulk purchase options, offering competitive solutions from our China-based operations.
The utility of Z-Pyr-OSu as a versatile synthetic intermediate is undeniable. Whether your work involves novel peptide drug discovery, advanced materials science, or diagnostic assay development, a dependable supply of high-quality Z-Pyr-OSu is essential. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to being that reliable source. We invite you to contact us to learn more about our Z-Pyr-OSu product line, discuss your specific application requirements, and explore how our manufacturing expertise can benefit your projects. Partner with us for your chemical intermediate needs.
Perspectives & Insights
Agile Reader One
“The NHS ester is a highly efficient leaving group, rendering the adjacent carbonyl carbon susceptible to nucleophilic attack.”
Logic Vision Labs
“This structural design makes Z-Pyr-OSu an excellent agent for activating carboxylic acids, facilitating the formation of amide bonds with amine-containing molecules.”
Molecule Origin 88
“This property is particularly leveraged in solid-phase peptide synthesis (SPPS) and solution-phase coupling reactions.”