The Chemistry of N-Methyl-p-toluidine: Synthesis and Applications
N-Methyl-p-toluidine (CAS 623-08-5) is an aromatic amine that holds significant importance in the field of fine chemicals. Its unique structure, featuring a methyl group on the para position of the aniline ring and a methyl group on the nitrogen atom, lends itself to a variety of chemical transformations. This makes it a valuable compound for research scientists and product formulators looking to develop new materials or enhance existing products.
The synthesis of N-Methyl-p-toluidine can be achieved through various routes, often involving the methylation of p-toluidine. For example, a common method involves the reaction of p-toluidine with methylating agents like iodomethane or dimethyl sulfate. Another potential pathway is the reduction of corresponding nitro compounds. The availability of multiple synthesis methods ensures that manufacturers can produce N-Methyl-p-toluidine efficiently to meet market demand. Companies seeking to buy this chemical can inquire about its production processes to ensure suitability for their specific applications.
The chemical properties of N-Methyl-p-toluidine are well-documented. With a molecular formula of C8H11N and a molecular weight of 121.18, it functions as a secondary amine. Its liquid state, with a boiling point of 212 °C and a melting point around -10.08 °C, along with a density of 0.958 g/mL at 25 °C, are critical parameters for its handling and application in chemical processes. The refractive index, n20/D 1.557, further characterizes its physical nature.
The applications of N-Methyl-p-toluidine are primarily centered around its role as a chemical intermediate. It is frequently employed in the synthesis of pharmaceuticals, agrochemicals, and specialized dyes. Its reactivity allows it to participate in coupling reactions, condensation reactions, and as a base in various organic transformations. Researchers often look for 'N-Methyl-p-toluidine for organic synthesis' when sourcing reagents for complex molecule construction.
For those in the industry looking to procure N-Methyl-p-toluidine, engaging with established manufacturers and suppliers, particularly from China, is a strategic approach. These suppliers can provide detailed product specifications, including purity levels (often 98% or higher) and CAS numbers (623-08-5), which are crucial for quality assurance. The ability to buy in various quantities, from laboratory samples to bulk industrial volumes, makes it accessible for a wide range of projects.
Safety is an integral part of working with N-Methyl-p-toluidine. As a toxic substance, it requires careful handling, appropriate ventilation, and the use of personal protective equipment. Suppliers must provide comprehensive Safety Data Sheets (SDS) that detail hazard statements, precautionary measures, and first-aid procedures. Understanding these safety aspects is vital for laboratory and industrial personnel.
In conclusion, N-Methyl-p-toluidine (CAS 623-08-5) is a fundamental fine chemical intermediate with a rich chemistry. Its synthesis, properties, and applications make it indispensable in many research and industrial settings. Sourcing this compound from reliable manufacturers, especially in China, ensures quality and facilitates the advancement of chemical innovation.
Perspectives & Insights
Alpha Spark Labs
“The availability of multiple synthesis methods ensures that manufacturers can produce N-Methyl-p-toluidine efficiently to meet market demand.”
Future Pioneer 88
“Companies seeking to buy this chemical can inquire about its production processes to ensure suitability for their specific applications.”
Core Explorer Pro
“958 g/mL at 25 °C, are critical parameters for its handling and application in chemical processes.”