The Chemistry of 1-Chlorohexane (CAS 544-10-5): Properties and Reactivity
1-Chlorohexane, a chemical compound denoted by CAS 544-10-5, belongs to the class of haloalkanes and is characterized by its molecular formula C6H13Cl. At room temperature, it presents as a clear, colorless liquid with a distinctive aromatic odor. Its molecular weight is approximately 120.62 g/mol. Understanding its physical properties is key to its industrial utility. It has a boiling point in the range of 133-134°C, a melting point of -94°C, and a density of 0.879 g/mL at 25°C. The compound is flammable, with a flash point of around 27°C (80°F), and its vapor pressure at 55°C is 53 hPa. Its solubility profile indicates it is largely insoluble in water but soluble in common organic solvents like ethanol and ether.
The chemical reactivity of 1-Chlorohexane is primarily governed by the presence of the chlorine atom attached to a primary carbon. This makes it susceptible to nucleophilic substitution reactions, where the chlorine atom can be replaced by a nucleophile. For instance, reaction with sodium hydroxide could yield hexanol, and reaction with sodium cyanide would produce hexanenitrile. It can also undergo elimination reactions, particularly in the presence of a strong base, to form alkenes, such as 1-hexene. These reactions are fundamental to its use as an intermediate in organic synthesis, allowing for the introduction of the hexyl moiety into other molecules.
The stability of 1-Chlorohexane is generally good under normal storage conditions, but it is incompatible with strong oxidizing agents and strong bases, which can lead to vigorous reactions. Its flammable nature also necessitates careful handling to prevent fire hazards. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. provide high-purity grades of 1-Chlorohexane, ensuring consistent reactivity and performance for synthesis applications. When procuring 1-Chlorohexane, understanding its chemical behavior is as important as its physical properties, particularly for chemists and process engineers designing synthesis routes.
The environmental impact of 1-Chlorohexane, including its potential for contributing to air pollution as a volatile organic compound (VOC), requires responsible handling and disposal. While specific biodegradation pathways exist, preventing its release into the environment is the primary goal. The consistent demand for 1-Chlorohexane in chemical synthesis underscores its importance. For businesses looking to buy 1-Chlorohexane, partnering with suppliers that offer quality assurance and detailed technical data is crucial for successful and safe chemical operations.
Perspectives & Insights
Silicon Analyst 88
“For instance, reaction with sodium hydroxide could yield hexanol, and reaction with sodium cyanide would produce hexanenitrile.”
Quantum Seeker Pro
“It can also undergo elimination reactions, particularly in the presence of a strong base, to form alkenes, such as 1-hexene.”
Bio Reader 7
“These reactions are fundamental to its use as an intermediate in organic synthesis, allowing for the introduction of the hexyl moiety into other molecules.”