Quinoline (CAS 91-22-5) is a fascinating organic compound with a distinct chemical profile that dictates its applications and handling requirements. For chemists, researchers, and laboratory personnel, a thorough understanding of its properties, reactivity, and safety protocols is essential for its effective and safe utilization. As a reputable supplier of high-purity chemicals, we aim to provide key insights into the chemistry of Quinoline.

Key Chemical Properties of Quinoline

Quinoline is characterized by several important physical and chemical properties:

  • Appearance: It is typically a light yellow to clear liquid, though it can darken to brown upon exposure to light or air over time.
  • Odor: It possesses a strong, characteristic, and somewhat unpleasant odor.
  • Solubility: Quinoline is slightly soluble in cold water but readily dissolves in hot water and most organic solvents, making it a versatile solvent.
  • Stability: While generally stable under recommended storage conditions, Quinoline is sensitive to light and moisture (hygroscopic). It can discolor upon prolonged exposure.
  • Reactivity: It is incompatible with strong acids, strong oxidizing agents, and certain other chemicals, which can lead to vigorous or hazardous reactions. It may react violently with materials like dinitrogen tetroxide and perchromates.
  • Combustibility: Quinoline is combustible and will emit toxic fumes, including nitrogen oxides, when heated or burned.

Safe Handling and Storage of Quinoline

Due to its chemical properties and potential hazards, proper handling and storage of Quinoline are critical:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves (e.g., nitrile), safety goggles or a face shield, and protective clothing when handling Quinoline. Work in a well-ventilated area, preferably under a fume hood.
  • Storage Conditions: Store Quinoline in tightly sealed containers, away from direct sunlight, heat, and incompatible materials. It should be kept in a cool, dry, and well-ventilated place, protected from moisture due to its hygroscopic nature.
  • Incompatibilities: Keep Quinoline separate from strong acids, oxidizing agents, and any other materials listed as incompatible to prevent hazardous reactions.
  • Spill Management: In case of a spill, contain the material immediately and absorb it with inert material. Dispose of waste according to local regulations.
  • Toxicity: Quinoline can be harmful if swallowed, inhaled, or absorbed through the skin. It is also an irritant to the skin and eyes. Long-term exposure may pose additional risks, including potential carcinogenicity. Always consult the Safety Data Sheet (SDS) for detailed toxicological information and first-aid measures.

Quality Considerations for Purchase

When purchasing Quinoline (CAS 91-22-5), whether for laboratory research or industrial production, verifying the quality and purity is essential. Ensure your supplier provides detailed specifications, including CAS number, purity percentage (e.g., 98%), and relevant analytical data. Understanding the typical impurities present and their limits is also important for sensitive applications. Always request the Safety Data Sheet (SDS) from your supplier before receiving or handling the product.

In conclusion, Quinoline (CAS 91-22-5) is a valuable chemical with diverse applications, but its handling requires diligence and adherence to safety protocols. By understanding its chemical properties and implementing proper safety measures, chemists and technicians can effectively and safely utilize this important organic intermediate. For reliable sourcing of high-purity Quinoline, consider partnering with experienced manufacturers who prioritize quality and safety.