In the realm of organic synthesis, particularly for Suzuki-Miyaura coupling, the selection of the appropriate boronic acid is critical for success. While many boronic acids are available, 4-Vinylphenylboronic Acid (CAS 2156-04-9) offers a unique combination of features that make it a preferred choice for specific applications. Understanding these distinctions helps researchers and procurement managers make informed decisions.

The Unique Advantage of 4-Vinylphenylboronic Acid

What sets 4-Vinylphenylboronic Acid apart is its dual functionality: the boronic acid moiety, essential for cross-coupling, and the reactive vinyl group. This vinyl functionality is not present in many common phenylboronic acid derivatives and opens doors to applications in polymer chemistry and materials science that are not easily achievable with simpler analogues. When seeking to buy 4-Vinylphenylboronic Acid, you are often looking for its capacity to introduce a polymerizable unit alongside the coupling capability.

Key Considerations for Selection:

  • Reactivity in Suzuki Coupling: Like other arylboronic acids, 4-Vinylphenylboronic Acid participates efficiently in Suzuki reactions. However, the electron-donating nature of the vinyl group can subtly influence reactivity compared to electron-withdrawing substituted phenylboronic acids.
  • Functional Group Tolerance: The stability of the boronic acid group under various reaction conditions is crucial. 4-Vinylphenylboronic Acid is generally stable, but specific reaction parameters should always be considered.
  • Availability and Cost: The price of boronic acids can vary significantly based on purity, scale, and supplier. Sourcing from a reliable manufacturer, often with competitive pricing structures, is essential.
  • Purity: For Suzuki coupling and especially for polymerization, high purity is non-negotiable. Impurities can inhibit catalysis or affect polymer properties. Always verify the purity specifications from your supplier.

When to Choose 4-Vinylphenylboronic Acid:

  • When your synthesis requires the incorporation of a styrene moiety.
  • If you plan to polymerize the resulting coupled product.
  • For applications in advanced materials, sensors, or electronic devices where the vinyl group's properties are beneficial.

Sourcing from a Trusted Partner

When you need to buy 4-Vinylphenylboronic Acid, consider a supplier with a proven track record in fine chemical intermediates. A reputable manufacturer, such as those based in China, can provide the necessary quality assurance and competitive pricing. Ensuring consistent quality from your supplier is key to replicating successful reactions and scaling up production efficiently.

By carefully evaluating the specific needs of your synthesis, you can confidently select the right boronic acid, with 4-Vinylphenylboronic Acid offering a distinct advantage for a wide range of innovative applications.