In the intricate field of peptide synthesis, the choice of coupling reagent can significantly impact the success of your project. Among the array of available reagents, O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate, commonly known as TSTU, has emerged as a highly effective and reliable option for peptide manufacturers and researchers. As a dedicated supplier and manufacturer of high-quality chemical intermediates, we understand the critical role TSTU plays in achieving optimal results.

TSTU's primary function is to activate carboxylic acids, transforming them into reactive N-succinimidyl active esters. These activated species then readily react with amines to form robust amide bonds, the very backbone of peptides. This process is characterized by its efficiency, leading to high yields and the formation of complete peptide chains. For procurement managers looking to buy TSTU, focusing on this efficiency translates directly into reduced reaction times and potentially lower production costs for pharmaceutical intermediates.

One of the significant advantages of TSTU, particularly relevant for scientists involved in complex peptide sequences, is its remarkable ability to minimize epimerization. Epimerization, the undesirable conversion of one stereoisomer to another, can compromise the biological activity and structural integrity of the synthesized peptide. TSTU, when used correctly, ensures that the stereochemical configuration of amino acid residues is largely preserved, a critical factor when sourcing high-purity peptide synthesis reagents. This makes it a preferred choice over some other coupling agents that may introduce higher levels of racemization.

Furthermore, TSTU demonstrates excellent selectivity. It preferentially reacts with amines even in the presence of other functional groups, such as hydroxyls. This selectivity is invaluable in multi-step synthesis where specific reactions need to be targeted without interference from other moieties. For R&D scientists, this translates to cleaner reaction profiles and simplified purification processes, ultimately saving time and resources.

The reagent is also noted for its effectiveness even under aqueous reaction conditions, which can be a distinct advantage in certain synthesis protocols. This flexibility in reaction conditions broadens its applicability across various research and manufacturing environments. When considering TSTU manufacturers, the ability to maintain efficacy in diverse solvent systems is a key indicator of quality and formulation expertise.

For businesses seeking a reliable TSTU supplier in China, it is paramount to partner with entities that guarantee product purity and consistent availability. The CAS number for TSTU is 105832-38-0, and it typically appears as a white to off-white powder. Its molecular formula is C9H16BF4N3O3, with a molecular weight of approximately 301.05 g/mol. Understanding these specifications is vital for bulk orders and integration into existing manufacturing workflows.

In summary, TSTU offers a compelling combination of efficiency, selectivity, and stereochemical control, making it a superior choice for peptide synthesis. As a leading supplier and manufacturer, we encourage procurement managers and research scientists to consider TSTU for their next project. We are committed to providing competitive TSTU prices and reliable supply to support your advancements in the pharmaceutical and biotechnology sectors. Contact us today to request a quote and explore how our high-quality TSTU can benefit your synthesis needs.