In the realm of biochemical research, precise and reliable peptide labeling is paramount. Whether for tracking molecular interactions, diagnosing diseases, or developing novel therapeutics, the choice of labeling reagent directly impacts the success of an experiment. Among the array of available options, N-(7-methoxycoumarin-4-acetyloxy)succinimide stands out as a high-quality choice for many applications.

N-(7-methoxycoumarin-4-acetyloxy)succinimide, often referred to by its acronym Mca-OSu, is a derivative of coumarin that possesses inherent fluorescent properties. Its structure features a succinimidyl ester group, which is highly reactive towards primary amines found in amino acids and proteins. This characteristic makes it an excellent candidate for covalent conjugation to peptides.

Why Choose N-(7-methoxycoumarin-4-acetyloxy)succinimide?

Several key attributes make Mca-OSu a preferred reagent for peptide labeling:

  • Fluorescent Properties: The coumarin core provides a fluorescent signal, allowing researchers to easily detect and quantify labeled peptides using standard fluorescence spectroscopy or microscopy. This is crucial for assays requiring sensitive detection.
  • Reactivity and Specificity: The succinimidyl ester group reacts efficiently with the N-terminal amino group or lysine side chains of peptides under mild physiological conditions, minimizing damage to the peptide structure. This ensures specific labeling.
  • High Purity: Sourcing N-(7-methoxycoumarin-4-acetyloxy)succinimide from reputable manufacturers, particularly those based in China, guarantees high purity (often 98% HPLC). High purity is critical to avoid non-specific reactions and ensure the integrity of the experimental results.

Sourcing and Availability

For procurement managers and researchers, identifying reliable suppliers is as important as selecting the right product. When looking to buy N-(7-methoxycoumarin-4-acetyloxy)succinimide, consider manufacturers that offer comprehensive product specifications and quality control data. The pricing can vary, so comparing quotes from different suppliers is advisable to secure the best price.

“We have found that partnering with manufacturers in China provides a cost-effective solution for sourcing high-purity biochemicals like Mca-OSu,” states a procurement specialist. “The ability to get a quote and arrange for samples from established suppliers is key to ensuring a stable supply chain for our research programs.”

For those seeking this essential reagent, exploring options from NINGBO INNO PHARMCHEM CO.,LTD. can lead to discovering dependable sources that offer competitive pricing and bulk purchase advantages. Ensuring a consistent supply of N-(7-methoxycoumarin-4-acetyloxy)succinimide is vital for uninterrupted research progress.