Selecting the correct silica gel is crucial for achieving optimal results in chromatographic separations. The properties of the silica gel, such as pore size, particle size, and surface area, directly influence the efficiency and resolution of the separation process. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated chromatography silica gel manufacturer, provides a diverse portfolio to meet varied scientific and industrial demands.

The pore size of silica gel is a key parameter, typically measured in Angstroms (Å). Standard silica gel for column chromatography commonly features a pore size of 60 Å, which is suitable for separating a wide range of organic molecules. Larger pore sizes, such as 100-200 Å or even larger, are often employed for the separation of larger molecules like proteins or peptides. When considering what silica gel is used for, the molecular weight and polarity of the target compounds are primary considerations.

Particle size, usually measured in microns (µm), also plays a significant role. Smaller particle sizes, typically in the 3-10 µm range, are used in HPLC to achieve higher efficiency and better resolution due to increased surface area and reduced path length for diffusion. For flash chromatography and open column chromatography, larger particle sizes, such as 40-63 µm or 63-200 µm, are often preferred as they offer lower back pressure, allowing for faster solvent flow and easier packing of columns.

The surface area and specific pore volume are other important characteristics. A larger surface area generally leads to better adsorption capacity and separation power. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its high purity silica gel for lab applications boasts optimized surface area and pore volume for superior performance. When you need to buy silica gel, understanding these specifications will guide you to the most effective product.

For specialized applications, NINGBO INNO PHARMCHEM CO.,LTD. also offers bonded silica phases, such as C18 or C8, which alter the polarity of the stationary phase and are essential for reversed-phase chromatography. The selection process should always align with the specific needs of your separation, whether it's for routine purification processes or advanced analytical challenges. Partnering with a knowledgeable chromatography silica gel manufacturer ensures you access the right materials for your success.