In the realm of organic chemistry, certain molecules serve as fundamental linchpins for complex synthesis. 2-Bromoethyl Isothiocyanate (CAS 1483-41-6) is one such essential intermediate, valued for its unique reactivity and broad applicability in creating sophisticated organic compounds. For R&D chemists, understanding its core properties and synthesis potential is key to leveraging its full capability. This article provides a comprehensive look at this compound, from its basic chemical identity to its significant roles in various synthetic strategies.

The Chemical Identity of 2-Bromoethyl Isothiocyanate

At its core, 2-Bromoethyl Isothiocyanate is defined by its molecular structure and properties:

  • Chemical Name: 2-BROMOETHYL ISOTHIOCYANATE
  • Synonyms: 2-Bromoethyl isothiocyanate, 1-Bromo-2-isothiocyanatoethane
  • CAS Number: 1483-41-6
  • Molecular Formula: C3H4BrNS
  • Molecular Weight: 166.04 g/mol
  • Appearance: Typically described as a colourless to yellow liquid.
  • Key Functional Groups: Features an isothiocyanate (-NCS) group and a primary alkyl bromide.

This combination makes it a bifunctional reagent, capable of participating in distinct chemical transformations. When looking to purchase this chemical, confirming these details with your supplier is a critical first step.

Applications in Organic Synthesis: Why It's Essential

The utility of 2-Bromoethyl Isothiocyanate in synthesis stems from its reactive isothiocyanate moiety and the bromoethyl group. It's a crucial intermediate for:

  • Formation of Heterocycles: The isothiocyanate group readily reacts with nucleophiles to form various sulfur- and nitrogen-containing heterocyclic rings, which are common in pharmaceuticals and agrochemicals.
  • Building Complex Molecules: The bromoethyl chain can be utilized for alkylation reactions, allowing for the introduction of the isothiocyanate functionality onto other molecules or the extension of carbon chains.
  • Bioconjugation and Chemical Biology: Its ability to covalently bind to nucleophilic residues in biomolecules makes it useful in protein labeling, enzyme assays, and other biochemical studies. Scientists often search for 'buy 2-bromoethyl isothiocyanate' for these research purposes.

Sourcing and Purity Considerations

For R&D chemists, obtaining 2-Bromoethyl Isothiocyanate with high purity (often stated as ≥98.0% assay) is vital for reliable experimental outcomes. When inquiring about this chemical, asking for a quote from a reputable manufacturer or supplier is recommended. Understanding the safety data, such as hazard statements, is also crucial for safe laboratory practice. As a leading supplier, we ensure that our 2-Bromoethyl Isothiocyanate meets the rigorous standards required by the scientific community, making it a dependable choice for all your synthesis needs.