When embarking on complex synthetic projects in organic chemistry, a thorough understanding of the properties of each reagent and intermediate is crucial. 1-Chloro-8-fluorooctane, bearing the CAS number 593-14-6, is one such vital compound that requires detailed examination of its characteristics. As a colorless liquid, its appearance is consistent with many linear halogenated alkanes, but its specific combination of chlorine and fluorine atoms on an eight-carbon chain imbues it with unique chemical behavior and utility.

The physical attributes of 1-chloro-8-fluorooctane are well-defined. Its density is approximately 0.939 g/cm³, and it possesses a boiling point of around 198.1°C at standard atmospheric pressure. The flash point, a critical safety parameter, is noted at 75.5°C, indicating it requires careful handling away from ignition sources. The refractive index, measured at 1.411, is another key identifier for quality control. These properties, meticulously documented, are not merely data points but are essential for predicting how the compound will behave during reactions, purifications, and storage. For example, its boiling point influences distillation techniques used to achieve the ≥99.0% purity that is often specified for its use as an organic synthesis intermediate.

The chemical reactivity of 1-chloro-8-fluorooctane is primarily dictated by the electronegativity and size of the halogen atoms. The carbon-fluorine bond is one of the strongest covalent bonds in organic chemistry, offering stability. Conversely, the carbon-chlorine bond is more reactive and can be selectively targeted in nucleophilic substitution reactions. This differential reactivity makes it an attractive starting material for chemists who need to introduce specific functional groups sequentially. When scientists are looking for where to purchase this intermediate, they often seek suppliers like Ningbo Inno Pharmchem Co., Ltd., known for providing compounds with consistent specifications, vital for repeatable experimental outcomes.

The role of 1-chloro-8-fluorooctane as a building block is substantial. It allows for the elongation of carbon chains and the incorporation of desirable properties associated with fluorination, such as increased lipophilicity or metabolic stability in potential drug candidates. Researchers often investigate various chemical properties of 1-chloro-8-fluorooctane to unlock new synthetic pathways or to develop novel materials with enhanced performance characteristics. The ability to selectively functionalize either the chloro- or fluoro-terminated end of the molecule provides immense flexibility in designing complex molecular architectures.

In summary, understanding the detailed physical and chemical properties of 1-chloro-8-fluorooctane is fundamental for its successful application in research and development. Its precise specifications, as provided by reputable suppliers, ensure that its potential as a versatile organic synthesis intermediate can be fully realized, driving forward advancements in chemistry.