In the intricate world of protein science, maintaining the correct redox state of cysteine residues is paramount. Disulfide bonds, formed by the oxidation of two thiol (-SH) groups, play critical roles in protein folding, stability, and function. However, for many experimental procedures, these bonds must be intentionally reduced to their constituent thiols. This is where powerful reducing agents like Dithioerythritol (DTE) come into play. As a leading supplier of biochemicals, NINGBO INNO PHARMCHEM CO.,LTD. provides high-quality DTE, enabling researchers to confidently buy and utilize this essential compound.

Dithioerythritol, identified by CAS number 6892-68-8, is a stereoisomer of the more commonly known Dithiothreitol (DTT), often referred to as Cleland's reagent. Both compounds function as effective reducing agents, but DTE offers specific advantages in certain applications. Its molecular formula, C4H10O2S2, highlights its two thiol groups, which are capable of reducing disulfide bonds (-S-S-) to two free thiol groups (-SH). In this process, DTE itself becomes oxidized, forming a cyclic disulfide.

One of the primary applications for DTE is in the biochemical laboratory for the quantitative reduction of disulfide bonds in proteins. This is crucial for techniques such as SDS-PAGE, where reducing agents are used to denature proteins by breaking any disulfide cross-links, allowing for accurate molecular weight determination. For scientists looking to buy DTE for these purposes, sourcing from a reliable manufacturer in China is key to ensuring product purity and consistent performance. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying DTE with an assay of ≥98.0%, meeting the stringent requirements of modern research.

Beyond protein studies, DTE also serves as a deprotecting agent for thiol-modified DNA. This application is vital in fields like synthetic biology and oligonucleotide synthesis, where precise control over functional groups is necessary. The ability of DTE to protect thiol groups from unwanted oxidation makes it an indispensable tool. When considering where to purchase DTE, focusing on suppliers who can provide detailed product specifications and reliable delivery is essential. Our company understands the critical nature of these biochemicals and strives to be a dependable partner for R&D professionals.

The efficacy of DTE stems from its ability to maintain a high concentration of reduced thiol groups in solution, effectively shifting the equilibrium towards the reduced state for disulfide bonds within proteins. This makes it a preferred choice for applications requiring robust disulfide bond cleavage. Researchers often seek competitive pricing for DTE, and by manufacturing and supplying directly from China, NINGBO INNO PHARMCHEM can offer advantageous pricing without compromising on quality. Whether you need DTE for enzyme stabilization, protein refolding, or sensitive analytical procedures, our product delivers the performance you require.

In summary, Dithioerythritol (CAS 6892-68-8) is a powerful and versatile reducing agent critical for a myriad of biochemical applications. Its role in protein chemistry and molecular biology is well-established. For researchers and procurement managers seeking a reliable DTE supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. stands ready to provide superior quality products at competitive prices. We encourage you to contact us to discuss your specific needs and to purchase DTE that will undoubtedly enhance your experimental outcomes.