For chemists and process engineers involved in complex organic synthesis, the selection of appropriate reagents and intermediates can significantly impact the success of a project. 1-(p-Toluenesulfonyl)-3-nitro-1,2,4-triazole (CAS 77451-51-5) is one such chemical that offers unique advantages in various synthetic applications, most notably in the field of oligonucleotide synthesis.

As a dedicated manufacturer and supplier of fine chemical intermediates, we understand the critical need for high-purity materials. 1-(p-Toluenesulfonyl)-3-nitro-1,2,4-triazole, typically supplied as a white to pale yellow crystalline powder, is valued for its role as a coupling reagent. Its ability to facilitate efficient bond formation is essential for building complex molecular structures with precision. The purity of this compound, often specified at ≥98% HPLC, is a testament to the rigorous manufacturing standards employed by reputable suppliers.

When sourcing this chemical, consider the expertise of the manufacturer. A company that specializes in producing such intermediates can offer valuable insights into its optimal use and handling. For example, understanding that it functions effectively as a coupling agent in processes like phosphotriester synthesis allows researchers to integrate it seamlessly into their workflows. Furthermore, inquiring about price and availability from manufacturers in China can provide a significant cost advantage, enabling larger-scale synthesis or more extensive research efforts.

The technical specifications of 1-(p-Toluenesulfonyl)-3-nitro-1,2,4-triazole, including its molecular formula (C9H8N4O4S) and molecular weight (268.25), are important for precise stoichiometric calculations in synthesis. Choosing a supplier that provides readily accessible Certificates of Analysis (COA) and Safety Data Sheets (SDS) ensures compliance and safe handling practices. By prioritizing these aspects when you buy this crucial intermediate, you empower your synthesis projects with a reliable and high-performing chemical component, ultimately driving innovation in your field.