Expert Insights: Using 4-Aminostyrene in Your Organic Synthesis Projects
For chemists engaged in organic synthesis, intermediates that offer versatile reactivity and well-defined properties are invaluable. 4-Aminostyrene (CAS: 1520-21-4), a compound featuring both an amine functionality and a polymerizable vinyl group, presents a unique set of opportunities for synthetic chemists. Whether you are developing new materials for electronics, pharmaceuticals, or other fine chemical applications, understanding the behavior and sourcing of this intermediate is key.
The Chemical Profile of 4-Aminostyrene
4-Aminostyrene (C8H9N) is characterized by its structure: a styrene backbone with an amino group attached at the para position. This dual functionality makes it a highly reactive and adaptable molecule. The amine group (-NH2) is nucleophilic and can participate in a variety of reactions, including acylation, alkylation, and condensation reactions. The vinyl group (C=C) is susceptible to addition reactions, polymerization, and can be involved in cross-coupling reactions. Its physical properties, such as being a yellow to red liquid or low melting solid with a purity of at least 97%, are important considerations for handling and reaction planning.
Synthetic Applications and Reactions
The reactivity of 4-Aminostyrene opens doors to numerous synthetic pathways. For instance, the amine group can be protected and then deprotected as needed during multi-step synthesis. It can also be diazotized to form diazonium salts, which are precursors to a wide array of transformations, including Sandmeyer reactions. The vinyl group is particularly useful for building extended conjugated systems or polymers. It can undergo radical or anionic polymerization, or it can be functionalized through reactions like hydroboration-oxidation or epoxidation. Researchers developing organic semiconductors for OLEDs or dye sensitizers for DSSCs often leverage these properties to construct molecules with specific electronic and optical characteristics. When planning your synthesis, consider how to buy 4-Aminostyrene from a reliable manufacturer to ensure consistent quality, which directly translates to predictable reaction outcomes.
Best Practices for Handling and Synthesis
Given its tendency to polymerize, especially when exposed to heat, light, or air, it is advisable to store 4-Aminostyrene under refrigeration (2-8°C) and in an inert atmosphere if possible. Inhibitors may be present in commercial samples to prevent premature polymerization. When performing reactions, it is often recommended to purify the material immediately before use, or to work with freshly opened, well-stored samples. If polymerization is a concern for your specific application, consider purchasing inhibited grades or adding a suitable inhibitor yourself. For chemists looking to buy 4-Aminostyrene for their projects, engaging with a chemical manufacturer that provides detailed handling instructions and technical support can be extremely beneficial. Our company is a trusted source for this versatile intermediate, offering both quality and expertise to support your synthetic endeavors.
Perspectives & Insights
Chem Catalyst Pro
“For chemists engaged in organic synthesis, intermediates that offer versatile reactivity and well-defined properties are invaluable.”
Agile Thinker 7
“4-Aminostyrene (CAS: 1520-21-4), a compound featuring both an amine functionality and a polymerizable vinyl group, presents a unique set of opportunities for synthetic chemists.”
Logic Spark 24
“Whether you are developing new materials for electronics, pharmaceuticals, or other fine chemical applications, understanding the behavior and sourcing of this intermediate is key.”