The development of novel chemical entities often hinges on the strategic use of highly reactive and functionalized intermediates. Among these, 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (CAS 17129-06-5) stands out as a particularly versatile reagent in advanced organic synthesis. This fluorinated ketone offers a unique combination of reactivity, stemming from its electrophilic carbonyl and its trifluoromethyl group, making it a valuable tool for chemists in both academic research and industrial applications.

From a manufacturing perspective, producing 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one involves controlled reactions that ensure high purity and consistency. Suppliers often highlight its utility in creating complex pyrazoles, substituted enones, and serving as a protecting agent in peptide synthesis. R&D scientists looking to buy this chemical often seek it for its ability to introduce fluorinated moieties, which can significantly alter the pharmacokinetic and pharmacodynamic properties of drug candidates or the performance characteristics of other advanced materials.

The handling and reactivity of this compound require careful consideration. As a flammable liquid with specific hazard statements, proper laboratory safety protocols are essential. When considering to purchase this intermediate, understanding its typical reactions – such as with organometallic reagents or phosphorous compounds – allows chemists to efficiently design synthetic routes. For procurement specialists, identifying manufacturers who can provide detailed technical data, including spectral information and safety data sheets (SDS), is paramount.

Many leading chemical manufacturers, particularly those specializing in fine chemicals and fluorinated compounds, offer 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one. These suppliers often provide various packaging options, from grams for laboratory use to kilograms and tons for industrial scale-up. When you plan to buy, seeking quotes from multiple providers will help you compare pricing and ensure you are getting the best value. A reliable supplier not only offers competitive pricing but also guarantees product quality and consistent availability, which are crucial for project continuity.

The ongoing advancements in synthetic chemistry mean that intermediates like 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one will continue to be in demand. Its ability to facilitate the creation of molecules with desirable fluorinated characteristics makes it a cornerstone reagent for many research and development projects. By understanding its synthesis applications and sourcing strategies, chemists and procurement managers can effectively leverage this powerful building block. For those looking to buy this intermediate, partnering with experienced manufacturers ensures a smooth procurement process and high-quality material for their critical synthetic endeavors.