Exploring 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene: Properties and Synthesis Applications
In the dynamic world of organic chemistry, certain compounds serve as critical linchpins, enabling the creation of complex and valuable molecules. One such compound is 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene, a halogenated aromatic compound with the CAS number 105529-58-6. This versatile intermediate, often sought from a reliable 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene supplier in China, is indispensable in various synthesis pathways.
The chemical structure of 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is key to its utility. Featuring a benzene ring substituted with bromine, fluorine, and a trifluoromethoxy group, it exhibits enhanced electron-withdrawing capabilities. This characteristic makes it highly reactive in essential organic reactions such as nucleophilic aromatic substitution and various cross-coupling reactions, including the widely used Suzuki-Miyaura coupling. These reactions are fundamental in constructing carbon-carbon bonds, a cornerstone of pharmaceutical and agrochemical development.
Physically, 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is typically a colorless to yellow liquid. It possesses a density of approximately 1.724 g/cm³, a boiling point around 78°C, and a flash point of 72.5°C. Its high purity, often exceeding 99.0%, ensures its effectiveness and reliability when used as an intermediate. When you buy 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene from a reputable manufacturer, you are investing in quality for your synthesis needs.
The primary application of this compound lies in its role as a building block for more complex organic molecules. In medicinal chemistry, the trifluoromethoxy group can enhance lipophilicity and metabolic stability, properties highly desirable in drug design. Similarly, in the agrochemical sector, these properties contribute to the efficacy and persistence of pesticides and herbicides. Industries that require high-performance CAS 105529-58-6 organic synthesis solutions often turn to experienced manufacturers and suppliers in China for consistent quality and competitive pricing.
Proper storage and handling are crucial to maintain the integrity of 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene. It should be stored in a cool, well-ventilated area, away from incompatible substances and ignition sources. Given its applications and the need for precise synthesis, sourcing this material from a dependable 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene manufacturer in China is a strategic advantage for many companies globally.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical intermediates like 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene. Our expertise in custom synthesis and process development ensures we can meet diverse client requirements, supporting innovation in pharmaceuticals, agrochemicals, and beyond.
The chemical structure of 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is key to its utility. Featuring a benzene ring substituted with bromine, fluorine, and a trifluoromethoxy group, it exhibits enhanced electron-withdrawing capabilities. This characteristic makes it highly reactive in essential organic reactions such as nucleophilic aromatic substitution and various cross-coupling reactions, including the widely used Suzuki-Miyaura coupling. These reactions are fundamental in constructing carbon-carbon bonds, a cornerstone of pharmaceutical and agrochemical development.
Physically, 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is typically a colorless to yellow liquid. It possesses a density of approximately 1.724 g/cm³, a boiling point around 78°C, and a flash point of 72.5°C. Its high purity, often exceeding 99.0%, ensures its effectiveness and reliability when used as an intermediate. When you buy 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene from a reputable manufacturer, you are investing in quality for your synthesis needs.
The primary application of this compound lies in its role as a building block for more complex organic molecules. In medicinal chemistry, the trifluoromethoxy group can enhance lipophilicity and metabolic stability, properties highly desirable in drug design. Similarly, in the agrochemical sector, these properties contribute to the efficacy and persistence of pesticides and herbicides. Industries that require high-performance CAS 105529-58-6 organic synthesis solutions often turn to experienced manufacturers and suppliers in China for consistent quality and competitive pricing.
Proper storage and handling are crucial to maintain the integrity of 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene. It should be stored in a cool, well-ventilated area, away from incompatible substances and ignition sources. Given its applications and the need for precise synthesis, sourcing this material from a dependable 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene manufacturer in China is a strategic advantage for many companies globally.
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality chemical intermediates like 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene. Our expertise in custom synthesis and process development ensures we can meet diverse client requirements, supporting innovation in pharmaceuticals, agrochemicals, and beyond.
Perspectives & Insights
Data Seeker X
“The chemical structure of 4-Bromo-2-fluoro-1-(trifluoromethoxy)benzene is key to its utility.”
Chem Reader AI
“Featuring a benzene ring substituted with bromine, fluorine, and a trifluoromethoxy group, it exhibits enhanced electron-withdrawing capabilities.”
Agile Vision 2025
“This characteristic makes it highly reactive in essential organic reactions such as nucleophilic aromatic substitution and various cross-coupling reactions, including the widely used Suzuki-Miyaura coupling.”