Understanding the fundamental chemical properties of reagents is the cornerstone of successful synthesis. Fmoc-N-Me-Gln(Trt)-OH, identified by its CAS number 1632075-13-8, is a compound that embodies this principle. With a molecular formula of C40H36N2O5 and a molecular weight of 624.72 g/mol, this derivative of glutamine offers a unique combination of functional groups that are indispensable in modern organic chemistry and biochemical research.

The structure of Fmoc-N-Me-Gln(Trt)-OH features several key protecting groups and modifications. The N-alpha-Fmoc (9-fluorenylmethoxycarbonyl) group is a standard protecting group in peptide synthesis, known for its stability under a range of conditions and its facile removal using mild bases like piperidine. This ensures that the amino terminus of the growing peptide chain remains protected until the desired step. The N-methylation on the alpha-nitrogen introduces a subtle but significant alteration to the amino acid backbone, which can impact peptide conformation and stability. Finally, the trityl (Trt) group on the side chain amide nitrogen of glutamine is a robust protecting group that shields the reactive side chain during peptide coupling, preventing unwanted reactions and ensuring stereochemical integrity.

NINGBO INNO PHARMCHEM CO.,LTD. offers this critical intermediate, understanding its value in diverse research applications. Its utility as a N-methylated amino acid derivative makes it particularly interesting for researchers aiming to fine-tune peptide properties. The presence of the trityl group highlights its suitability for complex synthesis where side-chain protection is essential, making it a prime choice for those looking for advanced chemical synthesis intermediates.

The compound's role as a building block is well-documented. Its application in the total synthesis of complex natural products showcases its ability to facilitate intricate molecular assembly. Beyond natural product synthesis, Fmoc-N-Me-Gln(Trt)-OH is crucial for creating modified peptides that can serve as potential therapeutic agents or probes for biological studies. Researchers often seek out specific amino acid derivatives for research to achieve targeted modifications and functionalities in their synthesized peptides, and this compound perfectly fits that need.

For laboratories engaged in drug discovery, sourcing reliable and high-purity reagents is non-negotiable. When planning projects involving custom peptide synthesis, having access to well-characterized building blocks like Fmoc-N-Me-Gln(Trt)-OH from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. streamlines the process and enhances the probability of success. The ability to confidently purchase Fmoc-N-Me-Gln(Trt)-OH ensures that researchers can focus on the experimental design and analysis rather than on reagent quality concerns.

In summary, Fmoc-N-Me-Gln(Trt)-OH is more than just a chemical; it is an enabler of scientific advancement. Its well-defined chemical properties and versatile applications underscore its importance in peptide chemistry and beyond. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply this vital compound, supporting the groundbreaking work of scientists worldwide.