Exploring the Chemical Properties of Bis(4-trifluoromethylphenyl)phosphine
Bis(4-trifluoromethylphenyl)phosphine, bearing the CAS number 99665-68-6, is a fascinating organophosphorus compound with a distinct set of chemical and physical properties that make it highly valuable in various scientific and industrial applications. Understanding these characteristics is key for chemists aiming to leverage its full potential in synthesis and catalysis.
At its core, Bis(4-trifluoromethylphenyl)phosphine (C14H9F6P) has a molecular weight of approximately 322.19 g/mol. Its structure features a central phosphorus atom bonded to two 4-(trifluoromethyl)phenyl groups. The trifluoromethyl (-CF3) substituents are strongly electron-withdrawing, significantly impacting the electronic environment around the phosphorus atom. This electron-deficient nature is a primary reason for its effectiveness as a ligand in transition metal catalysis, influencing reaction rates and selectivity. The compound typically appears as a white or off-white powder, indicative of its solid state under standard conditions, with a density around 1.317 g/mL at 25°C as reported in various chemical databases.
The chemical reactivity of Bis(4-trifluoromethylphenyl)phosphine is largely dictated by the phosphine moiety, which can readily coordinate with metal centers to form stable complexes. These complexes are often employed as catalysts in reactions such as cross-coupling, hydroformylation, and asymmetric synthesis. The stability imparted by the trifluoromethylphenyl groups contributes to the robustness of these catalytic systems, allowing them to function under demanding reaction conditions. When seeking to purchase this compound, acknowledging these properties helps in identifying the correct grades and specifications required for specific applications.
Suppliers of fine chemicals like NINGBO INNO PHARMCHEM CO.,LTD. often provide detailed technical data, including refractive index, boiling point predictions, and safety information, which further illuminate the compound's behavior. By understanding the inherent chemical properties of Bis(4-trifluoromethylphenyl)phosphine, researchers can make informed decisions about its use, ensuring optimal results in their synthetic strategies and catalytic explorations.
At its core, Bis(4-trifluoromethylphenyl)phosphine (C14H9F6P) has a molecular weight of approximately 322.19 g/mol. Its structure features a central phosphorus atom bonded to two 4-(trifluoromethyl)phenyl groups. The trifluoromethyl (-CF3) substituents are strongly electron-withdrawing, significantly impacting the electronic environment around the phosphorus atom. This electron-deficient nature is a primary reason for its effectiveness as a ligand in transition metal catalysis, influencing reaction rates and selectivity. The compound typically appears as a white or off-white powder, indicative of its solid state under standard conditions, with a density around 1.317 g/mL at 25°C as reported in various chemical databases.
The chemical reactivity of Bis(4-trifluoromethylphenyl)phosphine is largely dictated by the phosphine moiety, which can readily coordinate with metal centers to form stable complexes. These complexes are often employed as catalysts in reactions such as cross-coupling, hydroformylation, and asymmetric synthesis. The stability imparted by the trifluoromethylphenyl groups contributes to the robustness of these catalytic systems, allowing them to function under demanding reaction conditions. When seeking to purchase this compound, acknowledging these properties helps in identifying the correct grades and specifications required for specific applications.
Suppliers of fine chemicals like NINGBO INNO PHARMCHEM CO.,LTD. often provide detailed technical data, including refractive index, boiling point predictions, and safety information, which further illuminate the compound's behavior. By understanding the inherent chemical properties of Bis(4-trifluoromethylphenyl)phosphine, researchers can make informed decisions about its use, ensuring optimal results in their synthetic strategies and catalytic explorations.
Perspectives & Insights
Bio Analyst 88
“The chemical reactivity of Bis(4-trifluoromethylphenyl)phosphine is largely dictated by the phosphine moiety, which can readily coordinate with metal centers to form stable complexes.”
Nano Seeker Pro
“These complexes are often employed as catalysts in reactions such as cross-coupling, hydroformylation, and asymmetric synthesis.”
Data Reader 7
“The stability imparted by the trifluoromethylphenyl groups contributes to the robustness of these catalytic systems, allowing them to function under demanding reaction conditions.”