Exploring the Chemical Reactivity and Applications of 4-Iodopyrazole
At NINGBO INNO PHARMCHEM CO.,LTD, we are dedicated to understanding and supplying the chemical building blocks that drive scientific progress. Among these, 4-iodopyrazole (CAS 3469-69-0) stands out for its unique chemical reactivity and broad range of applications. This white to off-white crystalline powder is more than just a reagent; it's a gateway to synthesizing complex molecules with significant biological and material properties.
The core of 4-iodopyrazole's utility lies in its chemical structure. The pyrazole ring, a common motif in pharmaceuticals and agrochemicals, is functionalized with an iodine atom. This iodine atom is an excellent leaving group and a versatile handle for various cross-coupling reactions. For instance, Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling all readily employ iodinated aromatics and heterocycles like 4-iodopyrazole. These reactions are indispensable for creating new carbon-carbon bonds and constructing intricate molecular architectures.
The synthesis of 4-iodopyrazole itself is a field of interest for chemists aiming to produce it efficiently and with high purity. Understanding the various 4-iodopyrazole synthesis pathways allows manufacturers to optimize production, ensuring a consistent supply for researchers. Whether it's through direct iodination of pyrazole or other synthetic routes, the goal is to achieve the high purity (≥99%) that is critical for its use as a chemical intermediate.
The applications of 4-iodopyrazole extend across several domains. In medicinal chemistry, it serves as a precursor for drugs that inhibit specific enzymes, such as the c-Met inhibitors mentioned in scientific literature. Its role in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides demonstrates its potential in developing targeted therapies. Furthermore, its use in indium-mediated synthesis of heterobiaryls highlights its adaptability in creating complex biaryl systems.
For those looking to procure this essential chemical, inquiring about '4-iodopyrazole price' and '4-iodopyrazole CAS 3469-69-0' is the first step. NINGBO INNO PHARMCHEM CO.,LTD offers this compound with assured quality, supporting research and development efforts. By providing access to high-purity 4-iodopyrazole for organic synthesis, we enable chemists to explore new frontiers in molecular design and chemical innovation, solidifying its position as a vital component in the chemical industry.
Perspectives & Insights
Data Seeker X
“The pyrazole ring, a common motif in pharmaceuticals and agrochemicals, is functionalized with an iodine atom.”
Chem Reader AI
“This iodine atom is an excellent leaving group and a versatile handle for various cross-coupling reactions.”
Agile Vision 2025
“For instance, Suzuki-Miyaura coupling, Heck reaction, and Sonogashira coupling all readily employ iodinated aromatics and heterocycles like 4-iodopyrazole.”