NINGBO INNO PHARMCHEM CO.,LTD. is a leading supplier of high-quality chemical intermediates, and 2,3-Difluoro-5-methylbenzonitrile (CAS: 1003712-18-2) is a prime example of a compound critical to advanced chemical synthesis. This article explores its key chemical properties and common synthesis approaches, highlighting its importance as a versatile organic synthesis building block.

Chemically, 2,3-Difluoro-5-methylbenzonitrile is characterized by its molecular formula C8H5F2N and a molecular weight of approximately 153.13 g/mol. It typically presents as an off-white to white crystalline powder, with a high purity level often exceeding 99.0%. This purity is essential for its application as a reliable intermediate in sensitive chemical reactions. The presence of two electron-withdrawing fluorine atoms on the aromatic ring, alongside a nitrile group, significantly influences its reactivity. These features make it amenable to a wide range of organic transformations, including nucleophilic aromatic substitution, reduction of the nitrile to an amine, and various coupling reactions.

The synthesis of 2,3-Difluoro-5-methylbenzonitrile often involves multi-step processes starting from more common aromatic precursors. Typical routes may include fluorination reactions to introduce the fluorine atoms, followed by functional group transformations to install the methyl and nitrile groups in the desired positions. Optimization of these 2,3-difluoro-5-methylbenzonitrile synthesis routes is crucial for achieving high yields and purity, ensuring cost-effectiveness for industrial applications. As a significant pharmaceutical intermediate and a component in the development of fine chemicals, mastering its production is key.

Understanding these chemical properties and synthesis strategies allows researchers and manufacturers to effectively utilize 2,3-Difluoro-5-methylbenzonitrile in their projects. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing access to this vital compound, ensuring that the chemical industry has the building blocks necessary for innovation and product development. Our commitment to quality guarantees that clients receive a product that meets their exacting specifications for both research and large-scale manufacturing.